Pharm Cephalosporin

What is the mechanism of action for Cephalosporins?
- Beta-lactam antibiotic that inhibit formation of bacterial cell wall (typically Gr +)
- Binding to transpeptidase enzyme inhibiting the cross-linking of the peptidoglycan
What is Ceftaroline good against?

MRSA
What is Cefazolin good against?

MSSA
Which drug has the best activity against Bacteroides fragils?

Ceftoxitin
What is used to treat meningitis, Lyme Disease and gonorrhea?

Ceftriazone
What has good Pseudomona aeruginosa activity?
- Ceftazidime
- Cefepime
- Ceftazidime-avibactam
- Ceftolozan-tazobactam
What is Cefepime good against?

P. aeruginosa
What is Ceftazidime-avibactam good against?
- P. aeruginosa
- KPC producing E.coli and Kleb penumo activity
- Gr- ESBL activity
What is ceftolozan-tazobactam good against?
- P. aeruginosa
- Gr- ESBL activity
What is Ceftazidime good against?

P. aeruginosa
What is good against KPC producing E.coli and Kleb. Pneumo activity?

Ceftazidime-avibactam
What has good Gr- ESBL activity?
- Ceftazidime-avibactam
- Ceftolozan-tazobactam
True/False there are spectrum of beta lactams that work against MBL producing bugs

False; there are none

Author

lykthrnn

343194

Card Set

Pharm Cephalosporin

Description

NMSK Exam 2 Pharm

Updated

2018-10-26T01:58:04Z