Liver & GI Bleed

  1. List fxns of the liver
    • 1. Bile production
    • 2. Glucose metabolism
    • 3. Protein metabolism
    • 4. Lipid Metabolism
    • 5. Blood coagulation
    • 6. Detoxification
    • 7. Immunity
    • 8. Hormone Metabolism
  2. List 4 causes of hepatitis
    • 1. viral
    • 2. alcohol
    • 3. drugs
    • 4. autoimmune dz
  3. List s/s of increased portal pressure when there is impaired liver blood flow
    • Rash
    • Angeioedema
    • Arthritis
    • Fever
    • Malaise
  4. At what age should children receive the Hep A vaccine?
    What is the postexposure prophylaxis?
    Incubation time?
    • 1 year, then a booster 6-12 months later
    • Postexposure prophylaxis: Immune Globulin (IG)
    • Incubation: 2-5 weeks
  5. What is incubation period of Hep B?
    How are doses provided for its vaccine?
    What is the postexposure prophylaxis?
    • Incubation period: 2-5 months
    • Vaccine dosing: (Recombivax HB) Start with initial dose, then second dose 1 month later, and last dose 6 months after first dose
    • PEP: HBV Vaccine and Hep B Immune Globulin (HBIG) ideally within 24 hours of exposure
  6. What is incubation period of Hep C?
    What is the vaccine given?
    What is the percentage or likely hood it will develop into a chronic illness?
    • Incubation: 7 weeks and 15-20 year delay b/w infection and clinical manifestation
    • Vaccine: no vaccine
    • Percentage: 75%
  7. How is Hep D transmitted?
    What is the vaccine given?
    What is the incubation time?
    • Transmitted: only with Hep B virus infection
    • Vaccine: Provide Hep B vaccine
    • Incubation time: 1-6 months
  8. How is Hep E transmitted? 
    What is its incubation period?
    Prevention?
    • Transmitted: fecal-oral route, drinking water contaminated
    • Incubation: 3-6 weeks
    • Prevention: hand washing after toileting, clean water and food, wear gloves when handling stool
  9. List the three phases of hepatitis and time they last
    • 1. Preicteric Phase: 1-21 days
    • 2. Icteric Phase: 2-6 weeks
    • 3. Posticteric Phase: several months
  10. Match symptoms with hepatitis phase: malaise, HA, n/v, anorexia, fever, rash, tender liver



    A.
  11. Match s/s with hepatitis phase: Jaundice, light or clay-colored stools, dark urine, pruritis, GI symptoms



    B.
  12. Match hepatitis phase with s/s: fatigue, malaise, enlarged liver, anemia



    A.
  13. List diagnostics of hepatitis
    • Liver biopsy for chronic hepatitis
    • Liver enzymes (AST, ALT, LDH)
    • Bilirubin levels
    • Urine Urobilinogen
    • Albumin levels 
    • Viral antigens
  14. List the 4 types of cirrhosis
    • 1. Laennec's (alcoholism)
    • 2. Post necrotic
    • 3. Biliary
    • 4. Cardiac
  15. Match s/s of Cirrhosis if it's early, middle, or late stage: slight weight loss and farigue, unexplained fever, dull heaviness in RUQ, liver palpable, elevated liver enzymes



    B.
  16. State if this is early, middle, or late stage of cirrhosis: anorexia and n/v, diarrhea or constipation, flatulence, esophageal varices, anemia



    A.
  17. State if this is early, middle, or late stage of cirrhosis: decreased CBC count, jaundice with elevated bilirubin, decreased sex hormones (testicular atrophy and amenorrhea), palmar erythema, spider angiomas, peripheral neuropathy



    B.
  18. How can ammonia build up in the body with liver failure?
    Ammonia is produced when the body digests proteins. It is a toxin made harmless by the liver. 

    With liver failure, ammonia builds up, and may lead to hepatic encephalopathy in the brain.
  19. Do you lose water and sodium in cirrhosis or do you retain them?
    Retain
  20. List diagnostics of Cirrhosis
    • Labs: AST, ALT, LDH, Bilirubin, PT (all increased)
    •  - Total protein, CBC, Cholesterol (all decreased)
    • Liver scan, biopcy
    • Bilirubin in urine
  21. How is bilirubin managed by a healthy liver?
    • When Hb is broken down into "unconjugated bilirubin", it binds to albumin and transported to the liver
    •  - It is then "conjugated" making it water soluble
    •  - This conjugated bili is excreted in bile -> duodenum.
    •  - Once in the small intestine, bacteria metabolizes bili into "urobilinogen"
  22. List interventions for cirrhosis
    Diet
    What to avoid
    • Diet: high in carbs and vitamins
    •  - moderate to high proteins (low if ammonia levels are high)
    •  - Small, frequent meals
    • Avoid: alcohol and high fat foods
    • Others: rest or bedrest
  23. How will you manage anemia in cirrhosis pts?
    Give ferrous sulfate, PRBCs, and/or epogen
  24. How will you manage edema in cirrhosis patients?
    • Diuretics:
    •  - Lasix
    •  - Aldactone
    •  - HCTZ
    • Interventions: Na and Fluid restrictions
    •  - I/O
    •  - Daily weight
  25. How will you manage Ascites with a cirrhosis patient?
    • Similar to Edema, PLUS:
    •  - daily abdominal girth
    •  - IV albumin
    •  - Paracentesis
    •  - Peritoneal - venous shunt
  26. How will yo umanage Bleeding esophageal varices with a cirrhosis pt?
    Tests
    Meds
    Surgery
    • Tests:
    •  - Endoscopy: surgical ligation or sclerotherapy
    • Meds: 
    •  - Vitamin K
    •  - Vasoconstrictors (vasopressin)
    •  - Betablockers (propranolol)
    • Surgery: shunts
    •  - Portocaval shunt
    •  - Splenorenal shunt
  27. List management of hepatic encephalopathy
    • Low protein diet: 20-40G
    • avoid drugs & alcohol
    • Lactulose (laxative, but used also in management of portal-systemic encephalopathy (PSE))
    • Neomycin (decreases ammonia-producing bacteria in the gut)
    • Infection control
  28. List management of Hepatorenal syndrome
    What is the first priority intervention?
    • First: IV albumin
    • Diuretics
    • Na and Fluid restrictions
    • I/O and daily weights
  29. List s/s of UGI bleed
    • UGI: Melena or tarry stools is a slow bleed from UGI source
    •  - Coffee ground emesis
  30. List 3 tx goals of massive GI bleed
    • 1. Treat hypovolemic shock
    • 2. Prevent hypovolemia and lyte imbalance
    • 3. stop bleeding
  31. List nursing interventions with GI bleeds
    • 1. VS q15min for 1 hour
    • 2. strict I/O
    • 3. Blood replacement
    • 4. Foley
    • 5. Prepare for endoscopic procedure
    • 6. Lab test q4-6hours: CBC, BUN, PT LYTES, glucose
    • 7. Daily lab test: PT, liver enzymes
  32. List drugs to administer for GI bleed
    • Octreotide (Sandostatin)
    • HISTAMINE 2-receptor blockers (Cimetidine) or famotidine
    • Proton pump inhibitors - pantoprazoles
Author
edeleon
ID
342843
Card Set
Liver & GI Bleed
Description
ADN-D EXAM 3
Updated