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Neuroscience
The study of the nervous system
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Cognitions
are aware/conscious of these processes
occurs only in the mind (non-physical)
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Cognitive neuroscience
combination of cognitive psychology and neuroscience
relates mind and brain
how the mind and brain correlate or have a case and effect on each other
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Neurology
clinically oriented study and treatment of disorders of the nervous system
MD program
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Biopsychology
correlations and cause and effect between biological and cognitive processes
ex: hormone levels change in relation to stress of language learning program
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Physiology
function of biological system
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Anatomy
Study of the structure of biological tissue
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Temporal resolution
ability to solve resolve detail across time
ex. video camera (still images put together across time to form one moving image)
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Spatial resolution
ability to resolve detail across a given amount of space
ex. Camera not being able to see a fly bc the pixel is not small enough
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Invasiveness
level to which techniques are invasive to the subject
non invasive- not painful, no breaking of the skin
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Neuron
cell that makes up the nervous system and supports cognitive function
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Dendrite
branching structure that carry information from other neurons (they receive the neurotransmitters from the axon of the other neuron)
had terminals and collaterals
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Cell body (soma)
contains the cell organelles and cytoplasm
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How is the action potential fired?
- Neurotransmitter (glutamate) attaches to the protein receptor on the dendritic terminal
- Sodium ion channels open to allow sodium ions to flood the dendritic terminals
- The net charges of each dendritic terminal move to the cell body (the Na ions move to the soma)
- Na ions move to the soma where the Na+ voltage channels open (more voltage the more the channels open)
- Charge jumps along the axon to the Na + gates (myelin sheath speeds this along)
- When the sodium reaches the axon terminal it pushes the neurotransmitters into the synapse with electricity
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How long does an action potential last?
1 millisecond
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Myelin sheath
- Glial cell that wraps around the axon collateral to speed up AP by 10-100x its normal rate
- Myelin lines the collateral, but breaks in the sheath have sodium channels that the electric charge jumps to in order to speed up the AP
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Neuroglial cell
- Help support neurons
- Ex. give brain structure, provide nutrients
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Brain stem
- Responsible for basic functioning like breath regulation, blood pressure, basic instincts
- Pons, medulla, cerebellum
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Limbic system
- Basic mammalian functions
- Hippocampus, thalamus, hypothalamus, amygdala
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Cerebral cortex
- Advanced processes and behaviors, consciousness
- Frontal, parietal, occipital, temporal lobes
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White matter
made up of axons and glial cells
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Grey matter
Made up of cell bodies
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Corpus collosum
Made up of white matter and helps the two hemispheres communicate
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Ventricles
Filled with cerebrospinal fluid, which cushions the brain, transfers some signals, and helps bring snacks/take away waste
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Dura mater
The covering of the brain that protects it from hitting the skull
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Medulla
- Regulates vital functions
- Regulates breathing, swallowing, heart rate, and wake-sleep cycle
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Pons
- Link between cerebellum and cerebrum
- controls eye and body movement
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Cerebellum
- Important for dexterity and smooth movement
- Motor commands
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Thalamus
- Acts as a sensory relay between the sensory organs and the cortex
- Does not include smell
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Hypothalamus
- regulates body temperature, hunger and thirst, sexual activity, and endocrine functions
- Fight or flight response
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Hippocampus
learning and memory
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Amygdala
- detects threatening, fearful stimuli
- Emotions
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Parietal lobe
Sensory information for taste, touch, temperature
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Dorsal
Another way of saying inferior (top)
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Ventral
Another way of saying inferior (bottom)
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Medial
Close to the middle
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Lateral
Away from the middle
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Sagittal
Cut vertically and going through one of the hemisphere
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Coronal
Cut like a slice of bread
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Horizontal
(axial) cut horizontally through the brain
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When do posterior and dorsal refer to the same thing and when do they not?
When looking at a human, where the spine is vertical but the brain is horizontal, posterior and dorsal refer to the same thing. When looking at an animal with a horizontal spine, or just the brain itself, dorsal refers to the top of the brain and posterior refers to the back of the brain.
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hyperpolarized
greater disparity between inside and outside of the neuron
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Depolarized
The inside and outside of the neuron are closer in charge
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Action potential is also called
Axonal propagation
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Spike rate
- Measures how many times a neuron fires an AP per second
- Usually 5-500 spikes
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Rate coding
characterizes neuron behavior by how many times the AP fires in a second
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Neural code
- What the neuron is saying/what is being relayed through spike pattern
- neural code can be found through rate coding
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Temporal code
Requires recoding from multiple neurons at once
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Electrophysiology
Looks at the relationship between neuron function and the AP
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What is the difference between neuronal, neural, and neurological?
- Neuronal- only things directly involved with neurons
- Neural- neurons and glia
- Neurological- specifically disorders of the nervous system
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What are the two types of single cellular recording?
Intracellular and extracellular
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How is intracellular single cell recording done?
Ex vivo, you have to put the neuron on a petri dish and then put the electrode in
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How is extracellular single cell recording done?
In vivo, put the tip of the electrode just outside the neuron. Done with a stereotaxic frame
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How does an EEG work?
- Electrodes are placed on the brain and they measure the AP directly beneath them
- Restricted to the cortex
- Temporal resolution is real time
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Parietal lobe
- Middle of the brain
- Sensory information like pain
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Occipital lobe
Visual stimuli
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Frontal lobe
All higher reasoning and language skills
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Temporal lobe
Associated with hearing and being able to hear language
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