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Name the 4 types of Tissues
- 1. Muscle
- 2. Epithelial
- 3. Nervous
- 4. Connective
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Collections of specialized cells and the extracellular substance around them
Tissues
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The microscopic study of tissues
Histology
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Removal of tissues from a patient for diagnostic purposes
Biopsy
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examination of organs of a dead body to determine cause of death
Autopsy
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3 Germ Layers of Embryonic Tissue
- 1. Endoderm
- 2. Mesoderm
- 3. Ectoderm
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The inner layer of embryonic tissues, Forms lining of digestive tract and derivatives
Endoderm
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The middle layer of embryonic tissue, Forms tissues such as muscle, bone, blood vessels
Mesoderm
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The outer layer of embryonic tissue, Forms skin and neuroectoderm (nervous system)
Ectoderm
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Characteristics of Epithelial Tissue
- 1. Composed mostly of cells, little ground substance
- 2. Covers body surface, forms glands
- 3. Lines organs, blood vessels, body cavities
- 4. Distinct cell surface (apical)
- 5. Specialized cellular junctions
- 6. Avascular
- 7. Regeneration
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Major Functions of Epithelial Tissue
- 1. Protect underlying structure
- 2. Act as barrier
- 3. Permit the passage of substances
- 4. Secrete substances
- 5. Absorb substances
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How do you classify epithelial tissue?
Shape and # of layers
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Flat and scale like epithelium
Squamous
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Wide as they are tall epithelium
Cuboidal
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Taller than they are wide epithelium
Columnar
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One layer of epithelium
Simple
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Multiple layers of epithelium
Stratified
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Epithelium in which all cells touch the basement membrane, yet not all reach the apical surface
Pseudostratified Columnar
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Type of epithelium that allows diffusion of gases, filtration of blood, secretion, absorption
Simple
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Type of epithelium that involves protection, particularly against abrasion
Stratified
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Type of epithelium that allows diffusion or acts as filter
Squamous
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2 types of epithelium that are good for secretion or absorption. May include goblet cells that produce and secrete mucus.
Cuboidal and columnar
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a specialized extracellular matrix that acts as an adhesive to attach the epithelial cells to the connective tissue below
Basement membrane
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a loose connective tissue or dense irregular CT that has many different cells and blood vessels that nourish the epithelial layer.
Lamina Propria
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Where would you find simple squamous epithelium?
Lining of Blood vessels and heart
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Type of epithelial tissue that is good for diffusion, filtration, some secretion, and some protection against friction?
Simple Squamous Epithelium
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What tissue is in the Kidney tubules, glands and their ducts, choroid plexuses of the brain, lining of terminal bronchioles of the lungs, surfaces of the ovaries?
Simple cuboidal Epithelium
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What type of tissue is good for Secretion and absorption by cells of the kidney tubules; secretion by cells of glands and choroid plexuses; movement of particles embedded in mucus out of the terminal bronchioles by ciliated cells?
Simple cuboidal Epithelium
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What tissue is in the Glands and some ducts, bronchioles of the lungs, auditory tubes, uterus, uterine tubes, stomach, intestines, gallbladder, bile ducts, ventricles of the brain?
Simple Columnar Epithelium
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What type of tissue is good for Movement of particles out of the bronchioles of the lungs by ciliated cells;secretion by cells of the glands, the stomach, and the intestines; absorption by cells of the small and large intestines?
Simple Columnar Epithelium
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What tissue is Keratinized— primarily In the skin; nonkeratinized—mouth, throat, larynx, esophagus, anus, vagina, inferior urethra, cornea?
Simple Squamous Epithelium
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What type of tissue is good for Protection against abrasion, a barrier against infection, reduction of water loss from the body?
Simple Squamous Epithelium
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What tissue is found in the Lining of the nasal cavity, nasal sinuses, auditory tubes, pharynx, trachea, bronchi of the lungs?
Pseudostratified Columnar Epithelium
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What type of tissue is good for Synthesizing and secreting mucus onto the free surface; move mucus (or fluid) that contains foreign particles over the surface of the free surface and from passages?
Pseudostratified Columnar Epithelium
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What type of tissue is found in Lining of the urinary bladder, ureters, superior urethra?
Transitional Epithelium
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What tissue can Accommodate fluctuations in the volume of fluid in organs or tubes; protect against the caustic effects of urine?
Transitional Epithelium
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Cell junction that consists of adhesive glycoproteins that bind cells together and intracellular proteins attached to intermediate filaments that extend into the cytoplasm of the cells
Desmosomes
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This cell junction attach epithelial cells to basement membrane.
Hemidesmosome
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This cell junction hold cells together, form permeability barrier;prevents the passage of materials between cells
Tight junction
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This cell junction helps hold epithelial cells together, weaker than desmosomes.
Adherens Junction
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Type of cell junction that are protein channels that aid intercellular communication.
▪ Allows ions and small molecules to pass through.
▪ Coordinate function of cardiac and smooth muscle.
▪ May help coordinate movement of cilia in ciliated types of epithelium
Gap Junction
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These types of cell junctions anchor adjacent cells together and resist their separation during contractile activities
Adherens Junction and Desmosomes
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Glands with ducts that open to the outside surface
Exocrine Glands
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Glands that have no ducts, create hormones, and have no open contact with the exterior
Endocrine
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Type of exocrine gland that the vesicles empty their contents into the duct through exocytosis. Example: tears or sweat glands
Merocrine Gland
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Type of exocrine gland that a portion of the cell containing secretory products is pinched off the cell. Example: Mammary Gland
Apocrine Gland
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Type of exocrine gland that the entire cell is shed by the gland and become part of the secretion. Example: Sebaceous Gland (Hair)
Holocrine Gland
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What is the tissue that is most abundant; found in every organ; Consists of cells separated by extracellular matrix?
Connective Tissue
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Name the 7 functions associated with Connective Tissue
- 1. Enclosing and separating other tissues
- 2. Connecting tissues to one another
- 3. Supporting and moving parts of the body.
- 4. Storing compounds
- 5. Cushioning and Insulating
- 6. Transport for blood
- 7. Protection
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Cells in connective tissue that play an important role in inflammation. Have heparin and histamine enzymes that release to protect against infection.
Mast Cells
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Cell in CT that continuously move from blood vessels into connective tissues. The rate of movement increases dramatically in response to injury or infection.
White Blood Cells
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Large phagocytic cells in CT that play a mjor role in protection against infection, destroy dead or dying cells, & engulf foreign particles.
Macrophages
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fragments of hemopoetic cells containing enzymes and special proteins that function in the clotting process to reduce bleeding from a wound.
Platelets
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three major components of the ECM:
- (1) protein fibers,
- (2) ground substance,
- (3) fluid
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Three types of protein fibers—help form connective tissue.
- 1. collagen
- 2. reticular
- 3. elastic
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One of the protein fibers of the ECM--most abundant protein in the body; strong, flexible, inelastic
Collagen
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One of the protein fibers of the ECM--Fill spaces between tissues and organs. Fine collagenous, form branching networks
Reticular
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One of the protein fibers of the ECM--returns to its original shape after distension or compression. Contains molecules of protein elastin that resemble coiled springs
In the Skin, lungs, and arteries
Elastic
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Most common molecules in the ECM are called?
Ground Substance
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Ground Substance contains ____ which is a polysaccharide. Good lubricant. Vitreous humor of eye.
Hyaluronic Acid
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Ground Substance contains ____ which is a protein and polysaccharide. Protein part attaches to hyaluronic acid. Traps large amounts of water
Proteoglycan
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Ground Substance contains ____ ____ which hold proteoglycan aggregates together.
adhesive molecules
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The adhesive molecule in cartilage ground substance?
Chondronectin
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The adhesive molecule in bone ground substance?
Osteonectin
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The adhesive molecule in fibrous connective tissues' ground substance?
Fibronectin
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Embryonic connective tissue is called?
Mesenchyme
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3 Main Types of Adult Connective Tissue
- 1. Connective Tissue Proper
- 2. Supporting Connective Tissue
- 3. Fluid Connective Tissue
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What are the 2 types of Connective tissue proper?
Loose and Dense
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What are the 3 types of Loose Connective Tissue?
- 1. Areolar
- 2. Adipose
- 3. Reticular
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Which main category of CT consists of relatively few protein fibers that form a lacy network, with numerous spaces filled with ground substance and fluid?
Loose CT
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Consists of Cells within a fine network of mostly collagen fibers.
Areolar CT
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CT? Function: Loose packing, support, and nourishment for the structures with which it is associated
Areolar CT
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CT? Location: Widely distributed throughout the body; substance on which epithelial basement membranes rest; packing between glands, muscles, and nerves; attaches the skin to underlying tissues
Areolar CT
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CT that has little ECM surrounding cells
Adipose Tissue
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CT? Function: Packing material, thermal insulation, energy storage, and protection of organs against injury from being bumped or jarred
Adipose Tissue
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CT? Location: Predominantly in subcutaneous areas, in mesenteries, in renal pelvis, around kidneys, attached to the surface of the colon, in mammary glands, in loose connective tissue that penetrates spaces and crevices
Adipose Tissue
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Primary role of this fat is thermoregulation (non-shivering thermogenesis.) Prevalent in hibernating animals and newborns. Decreases with age?
Brown Fat
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CT that is mesh-like, supportive framework for soft organs?
Reticular Tissue
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CT? Function: Provides a superstructure for lymphatic and hemopoietic tissues
Reticular Tissue
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CT? Location: Within the lymph nodes, spleen, bone marrow
Reticular Tissue
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CT with Matrix composed of collagen fibers running in somewhat the same direction
Dense regular connective tissue
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CT? Function: Able to withstand great pulling forces exerted in the direction of fiber orientation; great tensile strength and stretch resistance
Dense Regular CT
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CT? Location: Tendons (attach muscle to bone) and ligaments (attach bones to each other)
Dense Regular CT
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CT with a Matrix composed of collagen fibers that run in all directions or in alternating planes of fibers oriented in a somewhat single direction
Dense Irregular CT
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CT? Function: Tensile strength capable of withstanding stretching in all directions
Dense Irregular CT
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CT? Location: Sheaths; most of the dermis of the skin; organ capsules and septa; outer covering of body tubes
Dense Irregular CT
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CT that is bone and cartilage—provides structure and strength to the body and protect soft tissues.
Supportive CT
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 Structure: Collagen fibers are small and evenly dispersed in the matrix, making the matrix appear transparent; the chondrocytes are around in spaces, or lacunae, within the firm but flexible matrix
Hyaline Cartilage
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Function: Allows the growth of long bones; provides rigidity with some flexibility in the trachea, bronchi, ribs, and nose; forms strong, smooth, yet somewhat flexible articulating surfaces; forms the embryonic skeleton
Hyaline Cartilage
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Location: Growing long bones, cartilage rings of the respiratory system, costal cartilage of ribs, nasal cartilages, articulating surface of bones, embryonic skeleton
Hyaline Cartilage
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Structure: the fibers are more numerous than in other cartilages and are arranged in thick bundles
Fibrocartilage
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Which cartilage? Function: Somewhat flexible and capable of withstanding considerable pressure; connects structures subjected to great pressure
Fibrocartilage
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Which cartilage? Location: Intervertebral disks, symphysis pubis, articular disks (e.g., knee and temporomandibular [jaw] joints)
Fibrocartilage
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Mature cartilage cells?
Chondrocytes
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Spaces in which the chondrocytes are located?
Lacunae
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Hard connective tissue composed of living cells (osteocytes) and mineralized matrix ?
Bone
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gives strength and rigidity; allows bone to support and protect other tissues and organs?
Matrix
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What 2 things is the bone matrix made of?
- 1. Collagen Fibers
- 2. Hydroxyapatite
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2 types of bone
- 1. Spongy
- 2. Compact or Dense
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Which type of bone? Function: Acts as scaffolding to provide strength and support without the greater weight of compact bone
Spongy
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Which type of bone? Location: In the interior of the bones of the skull, vertebrae, sternum, and pelvis; in the ends of the long bones
Spongy
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Which type of bone? Function: Provides great strength and support
Compact or Dense Bone
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Which type of bone? Location: Outer portions of all bones, the shafts of long bones
Compact or Dense Bone
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Which type of CT? Matrix: plasma ▪ Liquid and lacks fibers. ▪ Matrix formed by other tissues, unlike other types of connective tissue. ▪ Moves through vessels, but both fluid and cells can move in/out of the vessels
Fluid CT or Blood
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What are the 3 formed elements of Fluid CT or Blood?
red blood cells, white blood cells, and platelets
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Another name for red blood cells?
Erythrocytes
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Another name for white blood cells?
Leukocytes
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What forms blood cells and is found in bone marrow?
Hemopoietic Tissue
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What does the red bone marrow do?
Makes new blood cells
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What is the yellow bone marrow?
Adipose tissue, does not make new blood cells
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cell fragments involved in blood clotting
Platelets
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Type of CT? Function: Transports oxygen, carbon dioxide, hormones, nutrients, waste products, and other substances; protects the body from infections and is involved in temperature regulation
Blood or fluid CT
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CT? ▪Characteristics ▪ Contracts or shortens with force ▪ Moves entire body, pumps blood, or regulates the size of organs.
Muscle Tissue
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3 Types of Muscle Tissue
- 1. Skeletal
- 2. Cardiac
- 3. Smooth
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appear striated (banded); cells are large, long, and cylindrical, with many nuclei located at the periphery
Skeletal Muscle
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Type of Muscle Tissue that Moves the body; is Under voluntary (conscious) control?
Skeletal Muscle Tissue
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Type of muscle tissue that is located Attached to bone or other connective tissue?
Skeletal Muscle Tissue
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CT that are cylindrical and striated and have a single, centrally located nucleus; they are branched and connected to one another by intercalated disks, which contain gap junctions
Cardiac Muscle Tissue
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CT that Pumps the blood; is under involuntary (unconscious) control?
Cardiac Muscle Tissue
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CT Location: In the heart?
Cardiac Muscle Tissue
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cells are tapered at each end, are not striated, and have a single nucleus
Smooth Muscle Tissue
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Muscle Tissue? Function: Regulates the size of organs, forces fluid through tubes, controls the amount of light entering the eye, and produces “goose bumps” in the skin; is under involuntary (unconscious) control
Smooth Muscle Tissue
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Muscle Tissue?Location: In hollow organs, such as the stomach and small and large intestines
Smooth Muscle Tissue
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CT? consists of dendrites, a cell body, and a long axon; glia, or support cells, surround the neurons
Nervous Tissue
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Tissue that has the ability to produce action potentials?
Nervous Tissue
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Support cells of the neuron?
Glia
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cell process; conducts impulses away from cell body; usually only one per neuron
Axon
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cell process; receive impulses from other neurons; can be many per neuron
Dendrite
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3 types of membranes
- 1. Mucous
- 2. Serous
- 3. Synovial
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Which membrane Line cavities that open to the outside of body ▪ Secrete mucus ▪ Found in respiratory, digestive, urinary and reproductive systems?
Mucous membrane
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Which membrane Lines cavities not open to exterior ▪ Pericardial, pleural, peritoneal?
Serous Membrane
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Which membrane Line freely movable joints ▪ Produce fluid rich in hyaluronic acid?
Synovial Membrane
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What is the name for the heart cavity?
Pericardial
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What is the name for the lung cavities?
Pleural
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What is the name for the abdominal cavity?
Peritoneal
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What is the name for the thick layer of loose connective tissue that lines the Mucous membranes?
Lamina Propria
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What type of cell secretes mucus?
Goblet Cells
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