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Clinical Pharmacy
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The study of the
whole genome
in response to drug therapy
Pharmacogenomics
Individual gene-drug
interaction.
Study of role of genetics.
Pharmacogenetics
Single-gene, single disease
Mendelian Genetics
Naturally occuring
variants of gene structure
.
Gene Polymorphism
Genetic make-up/ Exact
pairing of alleles
Genotype
Expression of
traits
,
characteristics
as a result of genetic make-up.
Phenotype
FDA APPROVED PGENOMICS TESTS
TPMT - 6MP - Toxicity
CYP2D6 Tamoxifen - ↓ efficacy
Codeine - ineffective analgesia
UGT1A1 Irinotecan - Toxicity
Author
Haya
ID
342108
Card Set
Clinical Pharmacy
Description
PHARMACOGENOMICS
Updated
2018-09-02T14:56:27Z
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