Clinical Pharmacy

  1. The study of the whole genome in response to drug therapy
    Pharmacogenomics
  2. Individual gene-drug interaction.
    Study of role of genetics.
    Pharmacogenetics
  3. Single-gene, single disease
    Mendelian Genetics
  4. Naturally occuring variants of gene structure.
    Gene Polymorphism
  5. Genetic make-up/ Exact pairing of alleles
    Genotype
  6. Expression of traits, characteristics as a result of genetic make-up.
    Phenotype
  7. FDA APPROVED PGENOMICS TESTS
    • TPMT -    6MP           - Toxicity
    • CYP2D6  Tamoxifen   - ↓ efficacy

    •               Codeine      - ineffective analgesia
    • UGT1A1  Irinotecan   - Toxicity
Author
Haya
ID
342108
Card Set
Clinical Pharmacy
Description
PHARMACOGENOMICS
Updated