Which is the coagulant of choice for blood gas analysis?
C. lithium heparin
Given the following results, calculate the anion gap on this patient
Na: 140 mEq/L
K: 3.8 mEg/l
Cl: 105 mEq/L
Bicarbonate: 25 mmol/L
BUN: 10mg/L
Glucose: 110 mg/L
D. 10
Blood ammonia levels are usually measured in order to evaluate:
D. hepatic coma
Which of the following best represents the reference (normal) range for arterial pH
A. 7.35-7.45
Which of the following statements may be associated with the activity of insulin
A. stimulates glycogenesis in the liver
Acute myocardial infarction is more likely when
B. plaques destabilize and plaque contents are released
Elevation of serum creatine kinase may be associated with all of the following disorders except
A. bone disease
Creatinine is considered the substance of choice to measure endogenous renal clearance because
B. it is completely filtered by the glomeruli
As temperature increases, hemoglobin's affinity for oxygen
C. decreases
Decreased haptoglobin is a sign of
B. intravascular hemolysis
Lead levels are typically run on
C. whole blood
Indirect bilirubin may be quantified by reacting it initially with which reagent?
B. caffeine-sodium benzoate
Which assay using 24-hour urine is considered the best single screening test for pheochromocytoma?
B. metanephrines
A diabetic in ketoacidosis but no other evidence of disease or impairment has an osmolal gap greater than 10 mOsm/kg. This is because:
A. the ketones circulating in the blood are responsible for the osmolal gap.
Syndrome of inappropriate ADH is associated with
C. hyponatremia
Which of the following formulas estimates the VLDL cholesterol?
B. serum triglycerides divided by 5
In partition chromatography:
D. solutes are separated on the basis of their polarity
Given a sodium of 120, a glucose of 100 and a urea nitrogen of 10, what is the calculated osmolality of the person's serum
B. 249
Why is the "loading dose" of a drug different from the "maintenance dose"?
D. because a high dose is sometimes needed to quickly bring drug levels to within the therapeutic range
Ingestion of the following drug pairs increases their toxicity
D. ethanol and acetominophen
Urease is used to make ammonia that is reacted with glutamate dehydrogenase to make glutamate and NAD+. This allows the measurement of:
A. urea
Uric acid is derived from:
B. catabolism of purines
In cases of hepatocellular carcinoma, which protein synthesized by the liver is often increased?
D. alpha-fetoprotein
Which westgard multirule applies to a situation where one control point exceeds the mean by + 2 s and a second control point exceeds the mean by - 2s
A. 2 2s
ALT is used as a
A. screening test to detect hepatitis
In acute pancreatitis, a significant increase in which enzyme would be used for diagnostic purposes?
A. lipase
Which of the following conditions with increase total T4 by increasing TBG?
C. pregnancy
Which of the following techniques is used to identify the immunoglobulin class that is elevated in monoclonal gammopathies?
C. immunofixation electrophoresis
A urine microalbumin >30 is indicative of increased glomerular membrane permeability and a predictor of kidney failure
a. true
b. false
a. true
Which metabolite is an indicator of metabolic acid-base status?
C. HCO3
Hyperventilation leads to what type of acid-base status?
D. respiratory alkalotic
Which of the following statements regarding the clinical use of CK-MB is true?
B. immunoassays are more sensitive than electrophoretic methods to detect CK-MB
BNP is used as a stand alone indicator if congestive heart failure
a. true
b. false
b. false
Select the hormone that is associated with pituitary adenoma, amennorhea, and infertility in both men and women.
D. prolactin
Select two of the following methods considered the best methods to assay hormones.
a. mass spectrometry
b. immunoassay
c. HPLC
d. colorimetic enzyme assay
immunoassay/HPLC
The presence of only slightly visible hemolysis will significantly increase the serum level of which of the following electrolytes?
C. potassium
In serum protein electrophoresis, when the sample is placed in an electric field with a buffer of pH of 8.6, all the proteins
B. have a negative charge
MGUS, monoclonal gammopathy of undetermined significance, is characterized by all of the following except
A. treatment is recommended to prevent progression to multiple myeloma
IN chemiluminescent tested methods all of the following is true except
D. chemiluminesence is measured by spectrophotometer
Plasma proteins that increase in the acute phase response include
D. C-reactive protein, fibrinogen and alpha 1 glycoprotein
Primary and secondary Addison's disease can often be differentiated by plasma ACTH.
a. true
b. false
a. true
Select the best two answers. Troponin I
a. is an effective early marker for actue MI
b. is commonly differentiated from Tropinin T using electrophoresis
c. exceed CK-2 as a sensitive marker of acute MI
d. is only a late marker of heart disease or acute infarct
is an effective early marker for acute MI, exceed CK-2 as a sensitive marker of acute MI
Select the primary reagent used in the Jaffe method for creatinine
B. saturated picric acid and NaOH
If a test is very accurate it will:
B. consistently give an answer close to the true value for the analyte for a given specimen
Monitoring proficiency testing and competency is part of:
