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Caution: Federal Law PROHIBITS the transfer of this drug to any person other than the patient for whom it was prescribed.
Schedule 1, 2, 3, 4 Controls
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Shake Well before using
all suspensions, most asthma aerosol inhalers and nasal steroid sprays, lidocaine viscous topical liquid
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Refrigerate: for antibiotic suspensions
- amoxicillin (improves taste),
- cefpodoxime (Vantin),
- cefpozil (Cefzil),
- cefuroxime (Ceftin),
- ceftibuten (Cedax),
- cephalexin (Keflex),
- erythromycin/benzoyl peroxide gel (Benzamycin),
- erythromycin/sulfisoxazole,
- penicillin V
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Refrigerate: for others
- adalimumab (Humira),
- dronabinol (Marinol, Syndros),
- etanercept (Enbrel),
- calcitonin NS (Miacalcin),
- chlorambucil (Leukeran),
- ESAs (Epogen, Aranesp, Procrit),
- etoposide (VePesid),
- filgrastim (Neupogen),
- insulins (not opened),
- interferons (all),
- nystatin pastilles (Mycostatin),
- somatropin (Genotropin, Humatrope),
- lopinavir/ritonavir solution (Kaletra),
- alprostadil (MUSE, reconstituted Caverject),
- ritonavir softgels (Norvir),
- sandostatin (Octreotide),
- sirolimus solution (Rapamune),
- teriperatide (Forteo),
- thyrolar (Liotrix),
- lactobacillus (Visbiome),
- NuvaRing,
- promethazine suppositories,
- typhoid oral capsules (Vivotif Berna),
- formoterol (Foradil - pt can keep at room temp),
- dornase alfa (Pulmozyme - room temp if <24 hours)
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Refrigerate: eyedrops
- latanoprost (unopened Xalatan),
- tafluprost (Zioptan - good for 30 days in room temp if opened),
- trifluridine (Viroptic)
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For external use only
- topicals
- + may require: for the eye, for the ear, for the nose, for rectal, for vaginal, not to be taken by mouth
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IMPORTANT finish all this medication unless otherwise directed by prescriber
- antibiotics,
- antivirals,
- antifungals
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May cause drowsiness. May impair the ability to drive or operate machinery.
- analgesics with CNS effects,
- antipsychotics,
- some antidepressants: mirtazapine (Remeron),
- trazodone (Desyrel),
- dopamine agonists (ropinirole, etc.),
- antihistamines,
- antinauseants,
- anticonvulsants,
- muscle relaxants,
- antihypertensives with CNS effects,
- CII-V (2-5) depressant or narcotic drugs including hypnotics-controlled and non-controlled
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May cause blurred vision
- amiodarone,
- anticholinergics,
- ethambutol,
- hydroxychloroquine,
- isoniazid,
- isotretinoin,
- PDE 5 inhibitors (sildenafil, others),
- scopolamine patch,
- tamoxifen,
- telithromycin,
- voriconazole (VFEND),
toxic levels: digoxin yellow halos, alcohol, CNS depressants
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Do not use alcohol while taking this medicine
- disulfiram,
- tinidazole, metronidazole (avoid 48 hours after last dose),
- nitrates,
- opioids (all, special warning for Opana),
- tramadol,
- tapentadol (Nucynta),
- benzodiazepines,
- barbiturates,
- non-benzodiazepines hypnotics (zolpidem, etc.),
- anticonvulsants,
- antipsychotics,
- some antidepressants,
- skeletal muscle relaxants,
- insulin,
- metformin,
- sulfonylureas
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Avoid prolonged exposure to direct and/or artificial sunlight
- sulfa antibiotics,
- fluoroquinolones,
- tetracyclines,
- topical retinoids (newer ones less risk),
- isotretinoin (oral),
- ritonavir + few other HIV drugs,
- NSAIDs (piroxicam, diclofenac, some risk with ibuprofen, naproxen),
- metronidazole,
- isoniazid,
- diuretics
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Take on an empty stomach
- ampicillin,
- efavirenz (Sustiva/Atripla - preferably at bedtime),
- bisphosphonates (30 mins + before breakfast, 60 mins + for Boniva),
- captopril (1 hour before meals),
- didanosine (Videx),
- indinavir (Crixivan),
- iron (if tolerated),
- PPIs (variable times, all before eating),
- tadalafil and sildenafil (light meal, avoid fatty food),
- levothyroxine (30-60 mins before breakfast or 3-4 hours after last meal),
- Opana,
- mycophenolate (CellCept),
- tacrolimus extended release (Astagraf XL, Envarsus XR),
- voriconazole (VFEND),
- zafirlukast
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Take with food
- atazanavir (Reyataz),
- carvedilol (Coreg),
- itraconazole capsules,
- metformin (IR with breakfast and dinner, XR with dinner),
- lovastatin (with dinner),
- fenofibrate and derivatives (Lofibra, Lipofen, Fenoglide),
- niacin,
- gemfibrozil (Lopid - 30 min before breakfast and dinner),
- phosphate binders (when eating),
- NSAIDs,
- opioids (except Opana),
- steroids,
- metoprolol tartrate (Lopressor), lithium
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Take with full glass of water
- sulfamethoxazole/trimethoprim (Bactrim),
- bisphosphonates,
- sulfasalazine (Azulfidine + food)
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Do not eat/drink grapefruit/juice at any time
- lovastatin,
- simvastatin,
- atorvastatin,
- amiodarone,
- buspirone,
- carbamzepine,
- cyclosporine,
- tacrolimus,
- diazepam,
- triazolam,
- verapamil,
- nicardipine,
- felodipine,
- nisoldipine,
- nifedipine,
- telithromycin
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Danger in pregnancy
- ACE inhibitors,
- ARBs,
- renin inhibitors,
- carbamazepine,
- isotretinoin,
- lithium,
- NSAIDs,
- phenytoin,
- phenobarbital,
- topiramate,
- valproic acid,
- ribavirin,
- misoprostol,
- methotrexate,
- leflunomide,
- statins,
- dutasteride,
- finasteride,
- warfarin,
- lenalidomide,
- thalidomide
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May cause discoloration of the urine, skin, and sweat. May stain contact lenses and clothing.
- entacapone,
- levodopa,
- metronidazole,
- nitrofurantoin,
- phenazopyridine,
- rifampin,
- sulfasalazine,
- doxorubicin,
- mitoxantrone,
- propofol
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Check for peanut or soy allergy
- progesterone (Prometrium only),
- clevidipine (Cleviprex),
- propofol
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Separate from dairy products, calcium, magnesium or iron tablets, antacids
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Do not chew or crush, swallow whole
- enteric coated (bisacodyl, etc),
- any drug that ends with XR, ER, LA, SR, CR, CRT, SA, TR, TD,
- or has 24 in the name,
- or the ending "-cont" (for controlled release, such as MS Contin or Oxycontin),
- timecaps,
- sprinkles
- metoprolol XL and levodopa-carbidopa cut at score line (for half the dose), but cannot crush or chew
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Persistent diarrhea - due to colitis may occur weeks after using this medication - report to your doctor immediately if this occurs
- clindamycin,
- broad-spectrum antibiotics
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Warning: This medicine may make birth control less effective
- barbiturates (phenobarbital, etc.),
- St. Johns wort,
- some HIV drugs (some of the protease inhibitors, NNRTIs),
- ampicillin,
- tetracycline,
- rifampin,
- rifapentine,
- griseofulvin,
- anticonvulsants (topiramate, lamotrigine, carbamazepine, primidone, phenytoin, oxcarbazepine),
- bosentan
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