ABSITE ch 18 plastics skin soft tissue.txt

  1. Main cell type in epidermis; provide mechanical barrier
  2. Neuroectodermal cells in epidermis; transfer melanin to neighboring keratinocytes
  3. Primary structural proteins for the epidermis
  4. Antigen presenting cells in epidermis; role in type IV hypersensitivity reactions
    Langerhans cells
  5. Sensory nerves that detect pressure
    Pacinian corpuscles
  6. Sensory nerves that detect warmth
    Ruffini�s endings
  7. Sensory nerves that detect cold
    Krause�s end-bulbs
  8. Sensory nerves that detect tactile sense
    Meissner�s corpuscles
  9. Glands producing aqueous sweat
    Eccrine sweat glands
  10. Glands producing milky sweat
    Apocrine sweat glands
  11. Predominant collagen type in skin
    Type I
  12. Ability to regain shape
  13. Skin change caused by loss of tensile strength and elasticity
    Cushing�s striae
  14. Grafts including all epidermis and part of the dermis
    Split-thickness skin grafts
  15. Skin graft type with less contraction
    Full-thickness skin grafts
  16. Method of blood supply for skin graft for days 0-3
  17. Method of blood supply for skin graft for days 3+
  18. Tissue types unlikely to support skin graft (poorly vascularized)
    Tendon, bone, XRT areas
  19. Primary blood supply for TRAM flap
    Superior epigastric vessels
  20. Most important determinant of TRAM flap viability
    Periumbilical perforators
  21. Pressure sore with erythema and pain but no skin loss
    Stage I
  22. Pressure sore with partial skin loss and yellow debris
    Stage II
  23. Pressure sore with full-thickness skin loss and subcutaneous exposure
    Stage III
  24. Pressure sore involving bony cortex
    Stage IV
  25. Single best factor for protecting skin from UV radiation
  26. Rays responsible for chronic sun damage
  27. Disorder which predisposes patients to melanoma
    Xeroderma pigmentosum
  28. Most common site for melanoma
    Back (men), legs (women)
  29. Most common location for distant melanoma mets
  30. Least aggressive melanoma, with minimal invasion
    Lentigo maligna
  31. Most common type of melanoma, originating from sun-exposed areas
    Superficial spreading melanoma
  32. Most aggressive form of melanoma
  33. Aggressive melanoma type originating largely on palms and soles
    Acral lentigus
  34. Margin needed for thin melanoma
  35. margin needed for intermediate thickness melanoma
  36. margin needed for thick melanoma
  37. most common malignancy in US
    basal cell
  38. carcinoma originating from basal epithelial cells and hair follicles
    basal cell
  39. more aggressive type of basal cell carcinoma with collagenase production
    morpheaform type
  40. carcinoma of skin that often presents with overlying erythema, papulonodular with crust and ulceration
    squamous cell
  41. carcinoma that commonly develops in postradiation areas or old burn scars
    squamous cell
  42. risk factors for squamous cell carcinoma of skin
    actinic keratoses, xeroderma pigmentosum, bowen�s disease, immunosuppression, arsenic, coal tar, chlorophenols, nitrates, HPV, sun, fair skin, XRT
  43. risk factors for metastasis of squamous cell cancer
    poorly differentiated, greater depth, recurrent leasions, immunosuppression
  44. most common soft tissue sarcomas (2)
    malignant fibrous histiosarcoma, liposarcoma
  45. biopsy technique for sarcoma
    excisional if <4cm, longitudinal incisional if >4cm
  46. most common form of spread of sarcoma
  47. desired margins for sarcoma excision
  48. sarcomas requiring postop XRT
    high-grade, close margins, >5cm
  49. 5-year survival of sarcomas (after complete resection)
  50. common sarcomas in children; often proximity to vital structures precludes full resection
    head and neck sarcoma (ex: rhabdomyosarcoma)
  51. most common visceral and retroperitoneal sarcomas
    leiomyosarcomas, liposarcomas
  52. risk factors for angiosarcoma (2)
    PVC, arsenic
  53. Risk factor for lymphangiosarcoma
    Chronic lymphedema
  54. Vascular sarcoma involving skin, mucous membranes, or GI tract; assoc. w/immunocompromise
    Kaposi sarcoma
  55. #1 soft tissue sarcoma in children
  56. treatment of rhabdomyosarcoma
    excision, doxorubicin-based chemotherapy
  57. sarcoma originating from metaphyseal cells; increased incidence around knee
  58. soft tissue tumors associated with LiFraumeni syndrome
    childhood rhabdomyosarcomas, others
  59. soft tissue tumors associated with neurofibromatosis
    CNS tumors, peripheral sheath tumors, pheochromocytoma
  60. Soft tissue tumors associated with tuberous sclerosis
  61. Soft tissue tumors associated with gardners syndrome (2)
    Familial adenomatous polyposis, intra-abdominal desmoids
  62. Yellow deposits of cholesterol + histiocytes
  63. Growth with viral origin that can be contagious and autoinocuable
  64. Premalignant lesions in sun-exposed areas
    Actinic keratoses
  65. Non-premalignant lesion, can be pigmented darkly
    Seborrheic keratosis
  66. Skin lesion associated with squamous cell carcinoma
    Arsenical keratosis
  67. Neuroendocrine tumor with red/purple papulonodular indurated plaque
    Merkel cell carcinoma
  68. Proteins specific for merkel cell carcinoma (3)
    Neuron-specific enolase, cytokeratine, neurofilament protein
  69. Painful tumor composed of blood vessels and nerves; benign
    Glomus tumor
  70. Tumors commonly found in fascial planes, often anterior abdominal wall
    Desmoids tumors
  71. Squamous cell cancer in situ; 10% conversion rate to SCCA
    Bowen�s disease
  72. Rapidly growing lesion with central keratin-filled crater; involutes spontaneously over several months
  73. Disease associated with increased sweating
  74. Treatment of hyperhidrosis
  75. Infection of apocrine sweat glands, typically in axilla or groin
  76. Benign lesion with creamy keratin material within
    Epidermal inclusion cyst
  77. Benign lesion in scalp without epidermis
    Trichilemmal cyst
  78. Benign lesion over tendons; filled with collagenous material
    Ganglion cyst
  79. Benign lesion found along body fusion planes (midline abdomen, sacrum, occiput, nose)
    Dermoid cyst
  80. Congenital coccygeal sinus with ingrown hair
    Pilonidal cyst
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ABSITE ch 18 plastics skin soft tissue.txt
ABSITE ch 18