NOTE: Starting life with one cell then multiply rapidly
context: cell life
differentiation
day 1 = 1 cell type zygote
day 4 = 1 cell type morula
day 270 (birth) = ~300 cell types baby
day 5000 = ~300 cell types fully grown
day 15,000 = ~301 cell types older adult
NOTE: someone becoming someone else. extra one can be CANCER
context: cell life (TIME)
oocytes (eggs)
lifetime
context: cell life (TIME)
neurons
lifetime? (more connections)
You don't make new ones, you make new connections.
(more connections)
context: cell life (TIME)
muscle cells
lifetime? (more volume)
You don't make new ones, you stretch and bulk.
(more volume)
context: cell life (TIME)
bone cells
~25 years
context: cell life (TIME)
lymphocytes (WBC)
~1 year
context: cell life (TIME)
red blood cells (RBC)
~4 months
context: cell life (TIME)
skin cells
~1 month
context: cell life (TIME)
platelets
~10 days
context: cell life (TIME)
colon cells
~3 days
context: cell life (TIME)
stomach cells
~2 days
context: cell life (TIME)
spermatozoa
~2 days
T/F
cell death is not important to organism life
False!
context: methods of cell death
Necrosis or Apoptosis (programmed cell death)?
homocide
necrosis
context: methods of cell death
Necrosis or Apoptosis (programmed cell death)?
traumatic accident
necrosis
context: methods of cell death
Necrosis or Apoptosis (programmed cell death)?
old age or "seppuku"
apoptosis
context: methods of cell death
Necrosis or Apoptosis (programmed cell death)?
natural or purposeful
apoptosis
context: why die?
Necrosis or apoptosis?
physical/mechanical
necrosis
context: why die?
Necrosis or apoptosis?
lots of chemicals
necrosis
context: why die?
Necrosis or apoptosis?
lots of microbes invade
necrosis
context: why die?
Necrosis or apoptosis?
old age, mutations
apoptosis
context: why die?
Necrosis or apoptosis?
some chemicals
apoptosis
context: why die?
Necrosis or apoptosis?
some microbes invade
apoptosis
context: how die?
Necrosis or apoptosis?
fast death
necrosis
context: how die?
Necrosis or apoptosis?
kill and spill
necrosis
context: how die?
Necrosis or apoptosis?
slow death
apoptosis
context: how die?
Necrosis or apoptosis?
tag and bag
apoptosis
context: response
Necrosis or apoptosis?
inflammation
necrosis
context: response
Necrosis or apoptosis?
minimal
apoptosis
context: cell death process
necrosis or apoptosis?
small blebs form; the structure of the nucleus changes
necrosis
context: cell death process
necrosis or apoptosis?
the blebs fuse and become larger;
no organelles are located in the blebs
necrosis
context: cell death process
necrosis or apoptosis?
the cell ruptures and releases the cell's contents;
the organelles are not functional
necrosis
context: cell death process
necrosis or apoptosis?
small blebs form; no nucleus change
apoptosis
context: cell death process
necrosis or apoptosis?
the nucleus begins to break apart, and the DNA breaks into small pieces.
organelles located in blebs
apoptosis
context: cell death process
necrosis or apoptosis?
the cell breaks into several apoptotic bodies;
the organelles are still functional.
duh!
apoptosis (cause it says so lol)
remember things are still functional!!
where do new cells come from?
STEM CELLS! (booya)
with high replication rates too :D
2 major types of stem cells
1) totipotent (pre-blastocyst stem cells)
2) pluripotent (embryonic --> adult stem cells)
context: stem cells
totipotent
Each cell can develop into ANY cell type.
"Totally powerful"
context: stem cells
pluripotent
Each cell can develop into a LIMITED selection of cell types
what type of stem cell inside bone marrow?
what cell type does it make?
