Lewis Blood Group

  1. Secretor? Le(a-b+)
    Yes

    • 72% - W
    • 55% - B
  2. Secretor? Le(a+b-)
    No

    22% - W

    23% - B
  3. Secretor? Le(a-b-)

    & Percentage of population
    Yes or No

    6% - W

    22% - B
  4. Secretor & population for: 

    Le(a+b+)
    Weak secretor

    East Asia, Pacific
  5. What type of sugar does H, Se, and Le gene products have?
    • Fucosyltransferases
    • FUT1 = H
    • FUT2 = Se
    • FUT3 = Le

    *See pp: Blood Groups 560 wk 4, slide 15
  6. ABO, H, Se, & Le Expressions for: Le(a-b+) & major blood ABO blood groups (A,B,AB,orO)
    Genes Present: H, Le, Se

    Saliva Antigens: H (A,B), Lea, Leb

    RBC's (Le from plasma): H+, Le(a-b+)

    Se builds Leb onto Lea for H+ RBCs.

    Both  Lea and Leb in secretions
  7. ABO, H, Se, & Le Expressions for:
    Le(a+b-) & major blood ABO blood groups (A,B,AB,orO)
    • Genes Present: H, Le, se
    • Saliva antigens: Lea
    • RBC's (Le from plasma): H, Le(a+b-)

    *Le only builds Lea
  8. ABO, H, Se, & Le Expressions for:
    Le(a-b-) & major blood ABO blood groups (A,B,AB,orO)
    • Genes Present: H, le, Se
    • Saliva antigens: H(A,B)
    • RBC's (Le from plasma): H+, Le(a-b-)

    *No Lea, so no Leb
  9. ABO, H, Se, & Le Expressions for:
    Le(a-b-) as se & major blood ABO blood groups (A,B,AB,orO)
    • Genes present: H, le,se
    • Saliva antigens: -
    • RBC's (Le from plasma): H+, Le(a-b-)

    *No secretions*
  10. ABO, H, Se, & Le Expressions for:
    Le(a+b-) & Bombay patient
    • Genes Present: h,Le
    • Saliva antigens present: Lea
Author
Kwalke12
ID
340742
Card Set
Lewis Blood Group
Description
Lewis blood group
Updated