-
-
Secretor? Le(a+b-)
No
22% - W
23% - B
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Secretor? Le(a-b-)
& Percentage of population
Yes or No
6% - W
22% - B
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Secretor & population for:
Le(a+b+)
Weak secretor
East Asia, Pacific
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What type of sugar does H, Se, and Le gene products have?
- Fucosyltransferases
- FUT1 = H
- FUT2 = Se
- FUT3 = Le
*See pp: Blood Groups 560 wk 4, slide 15
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ABO, H, Se, & Le Expressions for: Le(a-b+) & major blood ABO blood groups (A,B,AB,orO)
Genes Present: H, Le, Se
Saliva Antigens: H (A,B), Lea, Leb
RBC's (Le from plasma): H+, Le(a-b+)
Se builds Leb onto Lea for H+ RBCs.
Both Lea and Leb in secretions
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ABO, H, Se, & Le Expressions for:
Le(a+b-) & major blood ABO blood groups (A,B,AB,orO)
- Genes Present: H, Le, se
- Saliva antigens: Lea
- RBC's (Le from plasma): H, Le(a+b-)
*Le only builds Lea
-
ABO, H, Se, & Le Expressions for:
Le(a-b-) & major blood ABO blood groups (A,B,AB,orO)
- Genes Present: H, le, Se
- Saliva antigens: H(A,B)
- RBC's (Le from plasma): H+, Le(a-b-)
*No Lea, so no Leb
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ABO, H, Se, & Le Expressions for:
Le(a-b-) as se & major blood ABO blood groups (A,B,AB,orO)
- Genes present: H, le,se
- Saliva antigens: -
- RBC's (Le from plasma): H+, Le(a-b-)
*No secretions*
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ABO, H, Se, & Le Expressions for:
Le(a+b-) & Bombay patient
- Genes Present: h,Le
- Saliva antigens present: Lea
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