What is MTOPS trial?
Medical Therapy of Prostatic Symptoms (MTOPS) Trial - The MTOPS trial, a prospective,randomized, double-blind, multicenter, placebocontrolled trial, was established to determine whether medical therapy can prevent or delay the progression of BPH in the long term. The results of the MTOPS trial suggest that the combination of doxazosin and finasteride exerts a clinically relevant, positive effect on rates of disease progression.Men who received combination therapy were significantly less likely to experience BPH progression than those receiving either monotherapy or placebo.