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neuro assessment objective data
- 1- mental status
- 2- cranial nerves
- 3- motor
- 4-sensory
- 5-cerebellar(balance and gait)
- 6- reflex
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glasscow coma scale
- -asses LOC
- -8 or less indicate coma
- -15 is high
- -3 is dead
- -eyes open, best verbal and motor responses
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TIA
- -risk factor for stroke or CVA
- -caused by focal brain, spinal cord or retinal ischemia
- -WITHOUT infarction of the brain
- -less than 1 hour
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ischemic stroke is a result of and results in
- -inadequate blood flow to the brain from artery occlusion
- -results in infaction(cell death)
-
severity of loss of function with stroke depends on
location and extent
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stoke assessment tool
- glasscow
- neuro
- physical and hx
-
thrombolytic stroke
injury to a blood vessel wall and formation of blood clot
-
thrombolytic stroke risk factor
- HTN and DM
- -no LOC for 24hrs
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embolic stroke
embolus lodges in and occuludes a cerebral artery resulting in infarction and edema
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embolic stroke risk factors
-afib, MI, heart disease
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embolic stroke S/S
- rapid onset
- S/S are less common
-
delirium
- -state of temporary but acute confusion
- -brain gets less o2
- -neurot abdormalitites
-
is delirium preventable and reversable
yes normally
-
risk factors for delirium
- -multiple
- -cholergenic deficiency
- -drug and ETOH abuse
- -post op
- -ICU
-
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dementia
dysfunction or loss of memory, orientation, attention, language, judgemnet and behavior
-
dementia key words
- chronic
- progressive
- decline in memory
- late onset
-
-
AD
- chronic and progressive neurodegenerative disease of the brain
- -most common form of dementia
-
AD patho
change in brain structure with amyloid plaques, neurofib tangles, loss of connection b/t neurons and neuron death
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AD genetics
- -early onset
- mutation w/ 1, 14 and 21
- -late onset
- inherited ApoE-$
-
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AD risks
- -doubled after 65
- -50% after 80
- -smoking, DM, htn, cardiac dysrhythmia, head trauma, age
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apraxia
diff w/ motor skills
-
-
agnosia
inability to recognize things
-
plaques
- -clusters of protein deposit b amyloid
- -cell membrane
- -memory and cognition
-
neurofib tangles
- -protein thread inside nerve cell
- -protein tau
- -cns
- -support intracellular structures
- -hold tubules together
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ischemic stroke diagnostics
- -MRI
- -non contrast(hemmorage)
- -CT angio(cerebral BV)
- -MRA(vascular lesion)
- -angiography
- -TCD(blood velocity)
- -lumbar puncture(RBC in CSF)
- -LICOX( brain o2 and temp)
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ischemic stroke labs
- -cbc
- -lipid
- -electrolyte
- -blood glucose
- -csf
- -renal/hepatic
-
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dysarthia
muscles for speech are weak
-
dysphasia
impaired ability to communicate
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aphasia
- receptive: loss of comprehension
- expressive: inability to produce language
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delirium diagnostics
- -med and phys hx
- -CAM
- -ECG
- -Drugs and ETOH
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delerium lab values
- CBC
- serum electrolyte
- -blood urea
- creatine
- liver/thyroid
- csf
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dementia diagnostics
- determine cause
- med, neuro, physc hx
- ct
- mri
- b12 and hypothyroidism
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ad diagnostics
- no definitive
- ct or mri
- pet
- csf
- b amyloid
- tau protien
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ischemic stroke clinical signs
- -motor deficit
- -communication
- -aphasia, dysphasia, dysarthia
- -opposite of affected hemisphere
- -affect
- -memory and judgement
- -elimination
-
delerium clinical signs
- hypo/hyper activity
- agitation
- hallucinations
- hours to days
- ABRUBT
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-
AD clinical signs
- cog
- progressive
- behavior
- dysphasia
- apraxia
- dysgraphia
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ischemic stroke drugs
- anticoagulant
- platelet inhibitors
- tPA
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tPA
- -produces localized fibrinolysis by binding to fibrin in thrombus
- -breaks down blood clot
- -iv
- -w/in 3-4 hours
- -reestablish blood flow and prevent cell death
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delerium drug therapy
- used cautiously
- sedation
- antiphyc meds
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dementia and AD drug therapy
- benzos
- cholinesterase inhibitors
- nmda
- antiphyc
- antidep
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benzos
- Ativan and valium
- -for sleep
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cholinesterase inhibitors
- -Aricept, razadyne, Exelon and cognex
- -decreased memory or cog
- -increases acetylcholinesterase at synapse
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nmda
- nameda
- for decreased memory and cog
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antiphyc
Risperdal, zyprexa
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antidepressant
Zoloft, luvox, celexa, Prozac, remeron, trazadone
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