cardio pathology

Imbalance between demand of O2 and supply

diastole.. so in tachycardia reduced filling time of coronary arteries making it susceptible for ischemia.

• 1. anterior portion of LV
• 2. Anterior 2/3rd of IVS
• 3. Apex

• 1. Posterior LV
• 2. Posterior 1/3rd IVS
• 3. Right Ventricle
• 4. Posteromedial papillary muscles
• 5. SA/AV nodes

Lateral wall of Left Ventricle

• Most common cause of death in US
• most common coronary artery disease.... Age is the most important risk factor. Males more commonly affected.

Chronic (stable) Angina

• Atherosclerotic Coronary artery  disease
• AV stenosis
• HTN with concentric LVH
• cocaine induced vasoconstriction
• hypertrophic cardiomyopathy

Subendocardial ischemia due to decreased coronary arterial blood flow or concentric hypertrophy.

• Exercise induced chest pain duration<20mins
• releived by rest or nitroglycerin

• Angina at rest
• may be due to disrupted plaques causing >70% blockade

• Vasospasm leading to transmural ischemia
• St segment elevation

• Non pharmacologic
• Wt loss, smoking cessation, low cholesterol diet, exercise
• {Pharmacologic
• Nitrates
• Beta blockers
• calcium channel blockers
• Aspirin
• Clopidogrel
• Ranolazine

Unexpected death due to cardiac cause within 1 hour after symptoms..... IHD is the most important risk factor but ventricular arrhythmia is the commonest cause of death

Most common cause: AV stenosis

COcaine