Ischemic Heart Disease?
Imbalance between demand of O2 and supply
Coronary arteries...when do they fill?
diastole.. so in tachycardia reduced filling time of coronary arteries making it susceptible for ischemia.
LAD... where does it supply?
1. anterior portion of LV
2. Anterior 2/3rd of IVS
RCA... Where does it supply?
1. Posterior LV
2. Posterior 1/3rd IVS
3. Right Ventricle
4. Posteromedial papillary muscles
5. SA/AV nodes
Left Circumflex... Supply?
Lateral wall of Left Ventricle
IHD...Angina pectorisjQuery1124026496961313132417_1522682019175? risk factor for angina?
Most common cause of death in US
most common coronary artery disease.... Age is the most important risk factor. Males more commonly affected.
Commonest type of Angina?
Chronic (stable) Angina
Causes of stable angina?
Atherosclerotic Coronary artery disease
HTN with concentric LVH
cocaine induced vasoconstriction
Pathogenesis of Stable angina?
Subendocardial ischemia due to decreased coronary arterial blood flow or concentric hypertrophy.
C/Fs of Stable angina?
Exercise induced chest pain duration<20mins
releived by rest or nitroglycerin
Angina at rest
may be due to disrupted plaques causing >70% blockade
Vasospasm leading to transmural ischemia
St segment elevation
treatment of angina?
Wt loss, smoking cessation, low cholesterol diet, exercise
calcium channel blockers
Sudden Cardiac Death?
Unexpected death due to cardiac cause within 1 hour after symptoms..... IHD is the most important risk factor but ventricular arrhythmia is the commonest cause of death
SCD in children?
Most common cause: AV stenosis
drug associated with AMI?