The immune system usually defends the body against foreign substances that are called?
Antigens
Memory is an important function of the immune system because it?
Allows faster future immune responses
Immunization with a vaccine works by?
producing active acquired immunity
B-cell lymphocyte is produced from?
It is derived from hematopoietic stem cell
A macrophage is a cell of the immune system that?
can be activated by lymphokines
Natural killer cells are part of the body's ____ immunity.
innate
In which type of immunopathology are the cells of the body NO longer tolerated and treated by the immune system as antigens?
A) Autoimmune disease
B) immunodeficiency
C) Hyperplasia
D) Hypersensitivity
B) Autoimmune disease
During anaphylactic type of hypersensitivity reaction, the plasma cells produce antibody called?
IgE
Which type of hypersensitivity reaction involves activated complement?
cytotoxic
what type of lymphocyte matures in the thymus, produces lymphokines and can increase or suppress humoral immunity?
T-cell lymphocyte
In the immune system, antibodies are proteins that are also called
immunoglobulins
which of the following types of immunologic disease involve a decreased number or activity of lymphoid cells?
immunodeficiency
humoral immunity involves the production of
antibodies
the diagnostic laboratory measurement of a specific antibody level in the blood is called
titer
which type of immunity may be provided immediately to dental personnel after needlestick accidents?
acquired passive immunity
which of the following situations would result in the least risk of drug allergy?
A) use with children
is involved in regulation of both humoral and cell-mediated immunity?
cell-mediated immunity
involved in the communication between lymphocytes within the immune system?
cytokines
which type of hypersensitivity reaction is referred to as delayed hypersensitivity
type IV
Dendritic cell is a specialized type inroad mucosa called a ?
Langerhans cell
What marker does the T-cytotoxic cell carry?
CD8
which of the general types of immunoglobulin is a major antibody found in blood serum and serves as the first passive immunity for the newborn?
IgG
most common cause of serum sickness?
penicillin
Which type of IgA present in both tears and saliva?
secretory
What type of hypersensitivity reaction involved in a fixed drug eruption when it occurs in the oral cavity?
type III
immune complex type
What is important for safety when using a live vaccine?
attenuated
cytokines?
include lymphokines and monokines
cells known to function as an antigen-presenting cell within the immune system?
B-cell lymphocyte
Macrophages
Dendritic cells
NOT T-cell lymphocytes
Interferon falls under the category of?
cytokines
Many small molecules can function as happens, which can be immunogenic in combination with larger molecules that function as
carriers
Examples of hypersensitivity reactions?
urticaria
angioedema
contact dermatitis and mucositis
NOT major aphthous ulcers
reactive arthritis is known for being?
an immunologic disorder
a target lesion on the skin is associated with which disease?
erythema multiforme
Tzanck cells are seen in which condition?
pemphigus vulgaris
the oral lesions in Reiter syndrome may resemble?
Erythema migrans
geographic tongue
aphthous ulcers are seen in ?
Behcet syndrome
ulcerative colitis
cyclic neutropenia
NOT Langerhans cell histiocytosis
The two cell types that microscopically characterize Langerhans cell histiocytosis are?
Eosinophils and Mononuclear cells
Name of the solitary bone lesion of Langerhans cell histiocytosis that may occur in the mandible?
Eosinophilic granuloma
Traditionally categories of Langerhans cell histiocytosis?
Hand-Schuller -Christian disease
Letterer-Siwe disease
Eosinophilic granuloma
NOT chronic disseminated reticulosis
the most distinct and definitive characteristic that distinguishes pemphigus from pemphigoid?
The histopathologic findings
The most characteristic oral manifestation of Sjögren syndrome is:
Xerostomia
desquamative gingivitis may be present in?
cicatricial pemphigoid
pemphigus vulgaris
lichen planus
NOT Aggressive periodontal disease
Which orofacial structures could create a life-threatening situation for the patient from angioedema involvement?
epiglottis
a pathologic condition producing a characteristic butterfly-shaped lesion on the face and oral ulcers, occurs more frequently in females than males, and for which the result of a blood test is important in its diagnosis?
lupus erythematosus
parts of body involved in Raynaud phenomenon?
fingers and toes
can be used in the management of herpetiform ulcerations?
topical tetracycline
most common location for Wickham striae in the intraoral region?
buccal mucosa
Pemphigus vulgaris?
condition is very serious and can be life threatening if untreated
Sawtooth-shaped epithelial rete ridges, degeneration of the basal cells of the epithelium, and a sandlike infiltrate of lymphocytes in the connective tissue subjacent to the epithelium are classic histopathologic features of?
Lichen planus
Acantholysis and Tzanck cells are associated with which condition?
Pemphigus vulgaris
Which of the conditions is very serious and can be life threatening if untreated?