this receptor acts in smooth muscle glands and has greater sensitivity to NE than EPI
alpha 1
activates phospholipase C which increases Ca2+
excitatory
alpha 1
this receptor is presynaptic and has a greater sensitivity to NE than EPI
alpha 2
decreases adenylate cyclase activity which decreases cAMP
excitatory and inhibitory
alpha 2
this receptors acts in hear muscle and kidney, the sensitivity for NE and EPI is equal
beta 1
increases adenylate cyclase activity which increases cAMP
excitatory
beta 1
this receptor acts in blood vessels and smooth muscles, the sensitivity to EPI is greater than NE
beta 2
increased adenylate cyclase activity which increases cAMP
inhibitory
beta 2
This receptor when stimulated will cause
contraction (vasoconstrict) ateriole smooth muscles
contraction (vasoconstrict) veins (smooth muscle)
secretion from salivary glands
contraction of pilomotor muscles
alpha 1
This receptor when stimulated will cause:
excitatory response in heart cells
renin secretion in kidney
beta 1
This receptor when stimulated will cause:
relaxation (vasodilation) vessels of skeletal muscles
relaxation (dilation) of bronchiole smooth muscle
relaxation of the uterus
relaxation of bladder smooth muscle
beta 2
Drug for non-obstructuve urinary retention
muscarinic agonist (simulates receptors)
example: bethanechol
Drug for vagal-induced fainting and dry secretions
muscarinic receptor antagonist (blocks receptor)
example: atropine
Drug for myasthenia gravis
Acetylcholinesterase inhibitors
example: neostigmine
Drug for nasal decongestion
alpha 1 agonists
example: phenylephrine
Drug for hypertension (2)
alpha 1 antagonist
example: prazocin
beta 1 antagonist
example:atenolol
Drug for relieving asthma attack (relaxes bronchiole SM)