-
Clindamycin IV dose
- 600 mg TID
- x 10 days for aspiration pneumonia
-
For aspiration pneumonia
Clindamycin 600 TID IV or Augmentin 875 BID x 10 days PO
-
Hospital acquired pneumonia
- Piptazo 4g QID IV
- linezolid 600 mg BID
-
Hospitalized CAP pt
- Azithromycin 500 mg BID
- with ceftriaxone 1 g QD
or Levofloxacin 750 mg QD
-
Pipericillin - tazobactam dose
- 4 g IV QID
- x 10 days for HAP
-
Ceftriaxone dose
- 1 g IV QD
- with macrolide for hospitalized CAP pt
-
Augmentin dose
- 875 BID
- x 10 days for aspiration pneumonia
-
linezolid dose
600 mg BID
-
Levofloxacin dose for pneumonia
- 750 mg QD x 10 days
- IV for hospitalized
- PO for outpatient w/recent hx of abx
-
What can stop pseudomonas
- piperacillin-tazobactam Zosyn
- ceftazidime
- 4th gen cephalosporins
- carbapenem
- quinolones
- aminoglycosides
-
What to use against atypical agents
- macrolides
- tigecycline
- tetracyclins
- moxifloxacin
-
what to use against anaerobes
- Augmentin
- Zosyn
- cefoxitin
- cefotetan
- carbapenems
- clindamycin
-
what bacterial lung infection is more common in smokers than non smokers
Hemophilus influenza
-
1st generation cephalosporins: 2 examples and two types of infections it combats
- Cephalexin, Cefazolin
- Gram +
- staph/strep (2nd choice to PCN)
-
2nd generation cephalosporins: 2 examples, and what organisms it combats
- cefotetan, cefoxitin
- anaerobes, Gram +/-
-
3rd generation cephalosporins: 3 examples and infections it combats
- Cefixime, ceftazidione, ceftriaxone (Rocephin)
- Gram -
- pseudomonas
- meningitis, nosocomial infections
-
4th generation cephalosporins: 2 examples, and coverage
- Cefepime, ceftaroline
- Pseudomonas
- Gram - /+
-
carbapenems: 2 examples
Meropenem, imipenem
-
What drug classes offer Gram +/- and pseudomonas coverage
- carbapenems
- 4th generation cephalosporins
- piperacillin-tazobactam (Zosyn)
-
covers gram - and pseudomonas
- Aztreonam
- aminoglycosides
- 3rd & 4th gen c-sporins, Zosyn, carbapenems, quinolones, fosfomycin
-
what covers Gram +/- and MRSA
- 5th generation cephalosporins
- TMP-SMX
- tigecycline
-
Tetracyclines are good for treating what infections?
- chlamydia
- rickettsia
- cholera
- h. Pylori
- Lyme
- CAP
-
side effects and warnings of tetracyclines
- Can’t be given with di- or trivalent minerals
- causes UV hypersensitivity
- not for children <9 (teeth)
-
azithromycin is good for treating what types of infections?
Lungs. Has long t 1/2 in tissues, so not good for blood infections
-
aminoglycosides are good choices against what microbes?
-
side effects and warnings of aminoglycosides
Does not get absorbed in GI tract. Good for endocarditis. Ototoxic, nephrotoxic
-
quinolones and macrolides can cause what
Prolonged QT interval
-
What antimicrobial can increase the action of warfarin?
Ciprofloxacin, sulfonamides
-
side effects and warnings of fluoroquinolones
Avoid caffeine and cation supplements
-
Which fluoroquinolone covers anaerobes
moxifloxacin
-
what drugs render pathogens unable to synthesize folic acid
sulfonamides
-
best choice for uncomplicated UTI
Sulfonamide
-
everything can cover Gram +s except...
- Aminoglycosides
- aztreonum
- colistin
-
most nosocomial PNA and UTI infections are Gram...
gram negative
-
sepsis protocol
- Within first three hours
- 1) measure lactate levels
- 2) obtain blood cultures
- 3) start broad-spectrum antibiotics
- 4) give 30 mL/kg normal saline or lactate
- within first 6 hours
- 5) vasoprerssors
- 6) measure SpO2 and central venous pressure
- 7) remeasure lactate level if originally high
-
maintain arterial pressure
65 or higher
-
Adult first line treatment for sinusitis
Augmentin 875 bid for 10 days
-
Second line treatment for pharyngitis
Bactrim DS qd x 10 days
-
treat strep pharyngitis in adults
Penicillin VK 500 mg bid x 10 days
-
Usual dose of Augmentin
875 mg BID x 10 days
-
Azithromycin dose for strep pharyngitis
500 mg qd x 3 days
-
clindamycin dose
- Oral 300 mg TID x 10 days
- IV 600 mg TID x 10 days
-
treat conjunctivitis
Erythromycin ointment QD x 5-7 days
-
Azithromycin dose
- 250 mg
- 2 on day one
- 1 on days 2-5
-
treat conjunctivitis in contact lens wearers
Ciprofloxacin Q 2 hours for two days then Q 4 hours for five days
-
Treat thrush
- fluconazole 100 mg QD x 7 days
- nystatin TID
-
Treat peritonsillar abscess
Augmentin 875 mg BID x 7 days
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