HIV

NRTI: Ziagen

NRTI: Epivir

NRTI: Emtriva

NRTI: Viread

NRTI: Retrovir

NRTI: Zerit

NRTI: Videx

NNRTI: Sustiva

NNRTI: Rescriptor

NNRTI: Viramune

NNRTI: Intelence

NNRTI: Edurant

PI: Prezista

PI: Reyataz

PI: Lexiva

PI: Crixivan

PI: Kaletra

PI: Viracept

PI: Invirase

PI: Aptivus

INSTI: Vitekta

INSTI: Tivicay

INSTI: Isentress

CCR5 Antagonist: Selzentry

Fusion Inhibitor: Fuzeon

Combination: abacavir + lamivudine

Combination: emtricitabine + TDF

Combination: emtricitabine + TAF

Combination: lamivudine + zidovudine

Combination: emtricitabine + TDF + efavirenz

Combination: emtricitabine + TDF + rilpivirine

Combination: emtricitabine + TAF + rilpivirine

Combination: emtricitabine + TDF + elvitegravir + cobicistat

Combination: emtricitabine + TAF + elvitegravir + cobicistat

Combination: lamivudine + abacavir + dolutegravir

Combination: atazanavir + cobicistat

Combination: darunavir + cobicistat

Name the class: 
Most require renal adjustment
No CYP interactions
Most have no regard to meal
BOX warning include: lactic acidosis and hepatomegaly with steatosis

Name the class:
No renal adjustment 
Most are CYP inducers
Hepatotoxicity and rash

Name the class:
No renal adjustment
Most are CYP inhibitors
Hepatotoxicity and rash
Metabolic abnormalities: hyperlipidemia, lipohypertrophy, hyperglycemia
CVD risk, ECG changes
Generally take with food

Name the class:
No renal adjustment
No major CYP interaction; but interact with polyvalent cations (separate dose)
Elevated CPK
Headache, insomnia
Most have no regard to food

The only NRTI that does NOT require renal dose adjustment. C/I with HLA-B*5701 positive due to severe hypersensitivity reactions. Usual dose: 300mg BID or 600mg daily. No regard to food

This NRTI has a lower dose regimen indicated for Hep-B. Common SE: N/V/D. Usual dose for HIV: 150mg BID or 300mg daily. No regard to food

Avoid combining this NRTI with lamivudine (both are cytosine analogs). Common SE: N/V/D, dizziness, headache, insomnia, hyperpigmentation (palm/soles), rash. Usual dose: 200mg daily with capsule. Refrigerate solution, stable x 3 months at RT. No regard to food

This NRTI carries warnings for renal toxicity +/- Fanconi syndrome, osteomalacia and decreased bone mineral density. Consider Vit.D+Ca supplementation. The powder should be mixed with soft food (applesauce/yogurt), NOT with liquid. Usual dose: 300mg daily

This NRTI is a new form of another NRTI, developed to reduce renal and bone toxicity. Only available in combination product, and NOT approved for treatment of chronic Hep-B. Known SE: nausea.

The only NRTI that also has IV formulation. BOX warning: hematologic toxicities and myopathy. Known to cause macrocytic anemia (monitor MCV) and elevated LFT. Avoid combining with stavudine (both are thymidine analogs). Usual PO dose: 300mg BID. No regard to food

This NRTI has BOX warning for pancreatitis. SE include peripheral neuropathy, elevated LFT, lipoatrophy and hyperbilirubinemia. Avoid combining with zidovudine and didanosine. Oral solution is stable x 30 days in refrigerator. Weight-based dose, Q12H. No regard to food

This NRTI has BOX warning for pancreatitis. C/I with allopurinol and ribavirin. SE include peripheral neuropathy, elevated amylase. Consider eye exam due to risk of optic neuritis. Avoid stavudine. Oral solution is stable x 30 days in refrigerator. Weight-based dose, daily. The only NRTI to be taken on EMPTY stomach

These two NRTIs should not be combined due to risk of pancreatitis and peripheral neuropathy