Viral Infections

  1. Tamiflu
  2. Tamiflu: 75mg BID x 5 days
    Treatment dose
  3. Tamiflu: 75mg daily x 10 days
    Prevention dose
  4. Rapivab
  5. Relenza
  6. These two neuraminidase inhibitors require renal dose adjustment
    • Tamiflu (oseltamivir)
    • Rapivab (peramivir)
  7. Concerns/warnings with neuraminidase inhibitors
    • Neuropsychiatric events
    • Serious skin reactions
    • Anaphylaxis
  8. This neuraminidase inhibitor is an inhaler and should not be used in asthma/COPD or with any breathing problems
    Relenza (zanamivir)
  9. This neuraminidase inhibitor is only available as an IV injection
    Rapivab (peramivir)
  10. Common side effect of this neuraminidase inhibitor is N/V/D, abdominal pain
    Tamiflu (oseltamivir)
  11. To be effective, these should be started within 48 hours of illness onset
    Neuraminidase inhibitors
  12. Flumadine
  13. Due to resistance, it's not rec'd for influenza prophylaxis and treatment of influenza A
    Flumadine (rimantadine)
  14. This herpes simplex virus (HSV) is most commonly associated with oropharyngeal disease
  15. This herpes simplex virus (HSV) is associated more closely with genital disease
  16. After occurrence of this virus infection, the virus lies dormant in the nerve root and can later cause herpes zoster infection, referred to as shingles
    Varicella zoster virus
  17. Zovirax, Sitavig
  18. Valtrex
  19. Famvir
  20. Zovirax cream and Sitavig are used for this
    Cold sores
  21. Infuse this antiviral agent over at least 1 hr and maintain adequate hydration to reduce risk of renal tubular damage
  22. Side effects of antivirals for HSV and varicella zoster virus include N/V/D, malaise, headache, elevated LFTs, especially increased seizure risk and elevated SCr with this IV agent
  23. Abreva
  24. Denavir
    Penciclovir topical cream
  25. Apply this OTC topical agent 5x daily at first sign of outbreak, and continue until healed
    Abreva (docosanol)
  26. Apply this Rx topical agent 5x daily x 4 days. It can also be used on genital sores
    Zovirax (acyclovir)
  27. Apply this Rx 50mg buccal tablet as a single dose to the upper gum region
    Sitavig (acyclovir)
  28. Apply this Rx topical agent every 2 hrs during waking hours x 4 days
    Denavir (penciclovir)
  29. Antiviral therapy should be initiated at the earliest sign or symptoms of this and is most effective when started within 72 hrs of onset of rash
  30. These 3 antivirals options are used for treatment of shingles
    • Acyclovir (Zovirax)
    • Valacyclovir (Valtrex)
    • Famciclovir (Famvir)
  31. This double-stranded DNA virus occurs in advanced immunocompromised states and most commonly causes retinitis, colitis, or esophagitis
    Cytomegalovirus (CMV)
  32. These 2 antivirals are treatment of choice for CMV
    • Ganciclovir (Cytovene)
    • Valganciclovir (Valcyte)
  33. These 2 antivirals are reserved for refractory cases of CMV
    • Foscarnet (Foscavir)
    • Cidofovir (Vistide)
  34. Ganciclovir IV should be prepared in _____ and not _____
    Sterile water, not bacteriostatic
  35. The suspension formulation of this antiviral should be refrigerated and discard after 49 days
    Valganciclovir (Valcyte)
  36. This antiviral agent can cause retinal detachment, routine eye exam should be considered
    Valganciclovir (Valcyte)
  37. Side effects of ganciclovir and valganciclovir include N/V/D, fever, anorexia and these, which is why CBC w/differential, platelets should be monitored
    • Thrombocytopenia
    • Neutropenia
    • Leukopenia
  38. Cidofovir (Vistide) has BOX warning for this, patient should receive hydration before each dose
  39. Foscarnet (Foscavir) has BOX warning for renal impairment and this, which is due to electrolyte imbalances
  40. The infection of this virus is called "mononucleosis" or "mono".  Transmitted through bodily fluids (primarily saliva), and can spread by kissing.  Symptoms include fever, fatigue, sore throat, swollen lymph nodes.  No drug treatment or vaccine exists. Usually resolve in 2-4 weeks
    Epstein-Barr Virus (EBV)
Card Set
Viral Infections
Viral treatment