Adrenal Insufficiency

  1. Adrenal context of adrenal gland produces three hormaones?
    • Glucocorticoid (cortisol)
    • Mineralocorticoid (aldosterone)
    • Sex hormone (androgen)
  2. What dose Glucocorticoid do?
    (There are three.)
    • 1. Regulate carbohydrate, fat, protein
    • 2. Decrease inflamation
    • 3. Tolerate stress
  3. What does mineralocorticoids do?
    Maintain sodium and potassium balance
  4. Adrenal medulla of adrenal gland produces?
    Epinephrine and norepinephrine
  5. What do epinephrine and norepinephrine control?
    • They control:
    • - blood pressure
    • - myocardial contractility
    • - general metabolism
  6. Adrenocorticol insufficiency is when cortisol hormone is insufficient. What are primary and secondary adrenocorticol insufficient?
    Primary adrenocorticol insufficient is caused by factors (autoimmune disease, infection...) that destroy the adrenal gland.

    Secondary adrenocorticol insufficient is cased by exogenous corticosteroid that decrease the work of hypothalamus, anterior pituitary gland, or pathology of those organs
  7. What time does the cortisol hormone reach the heighest level?
    in the morning
  8. Who usually get external corticosteroid (aka steroid therapy)?
    • Patients with:
    • - arthritis
    • - transplanted organs
    • - allergic/ autoimmune disease
    • - sever asthma
    • - kidney disease
  9. What is the syndrome in patient with chronic adrenal insufficiency?
    And what are four importances characteristic?
    • Cushing syndrome:
    • - moon face
    • - buffalo hump
    • - muscle wasting (แขนขาลีบ)
    • - hirsutism (ขนดก)
  10. What are four potential problem in pt with chronic adrenocorticol insufficiency?
    • 1. Stress intolerance
    • 2. Delay healing
    • 3. Susceptibility
    • 4. Hypertension
  11. What happens when pt get adrenal crisis?
    • high fever
    • nausea, vomiting 
    • postural hypotension
    • hypoglycemia leading to unconcious
  12. Which medication we use to manage adrenal crisis?
    Hydrocortisone
  13. Which patients are at risk of adrenocorticol insufficient?
    • Rule of 2s :
    • taking 20 mg/day of cortisol for 2 weeks within past 2 years
  14. What are dental management for the pt with the possibility of adrenocorticol insufficient?
    Consult physician - patient may need steroid supplement
Author
Bentley
ID
337331
Card Set
Adrenal Insufficiency
Description
Source: CMU (Aj. Nushada)
Updated