TB

Rifadin

Rifamate

Rifater

Myambutol

Part of RIPE therapy for active TB, this agent is an INDUCER

This agent is an INHIBITOR

These two agents require renal adjustment

These two agents from RIPE should be taken on an EMPTY stomach

Usual dose is 10 mg/kg. Max: 600mg PO daily

Usual dose is 5 mg/kg. Max: 300mg PO daily

Side Effects: elevated LFTs, orange-red discoloration of body secretions, flu-like syndrome, positive Coombs test

Side Effects: elevated LFTs, DILE, peripheral neuropathy, positive Coombs test

Side Effects: elevated LFTs, hyperuricemia, gout, GI upset, malaise

Side Effects: elevated LFTs, optic neuritis (dose-related), decreased visual acuity

Avoid this agent from protease inhibitors (a C/I)

Store the oral solution of this agent at room temperature

Pyridoxine 25mg PO daily is usually prescribed to decrease risk of this drug-associated peripheral neuropathy

This agent is preferred for HIV+ patients, pregnant women, and children

This is used as substitution for rifampin to avoid DDI with protease inhibitors