1. Dextroamphetamine
    (CNS) stimulant that acts by releasing norepinephrine from nerve endings. The client should take the medication at least 6 hours before going to bed at night to prevent sleep disturbance.
  2. Edrophonium (Enlon) is a short-acting (30 minutes) acetylcholinesterase inhibitor used as a diagnostic agent.
    • When a client has suspected myasthenia gravis, the health care provider will administer an edrophonium test. When a dose is administered intravenously, an increase in muscle strength should be seen in 30 to 60 seconds. If no response occurs, another dose of edrophonium is given over the next 2 minutes, and muscle strength is tested again. If no increase in muscle strength occurs with this higher dose, the muscle weakness is not caused by myasthenia gravis.
    • Clients receiving injections of this medication commonly demonstrate a drop in blood pressure, feel faint and dizzy, and are flushed.
  3. Ergotamine can produce vasoconstriction
    The nurse periodically assesses for hypertension; cool, numb fingers and toes; muscle pain; and nausea and vomiting. This medication does not cause hypotension, constipation, or dependent edema
  4. The client should not receive cyclobenzaprine if the client has taken monoamine oxidase inhibitors such as tranylcypromine or phenelzine within the last 14 days. Otherwise, the client could experience hyperpyretic crisis, seizures, and possibly death.
  5. Grapefruit juice can increase peak and trough levels of carbamazepine
  6. Tramadol can precipitate a hypertensive crisis if combined with an MAOI.

    Its use is not contraindicated with beta blockers, histamine H2 antagonists, or calcium channel blockers.
  7. Carmabazine
  8. Amantadine is an antiparkinson agent
    potentiates the action of dopamine in the central nervous system. The expected effect of therapy is a decrease in akinesia and rigidity. Urinary retention, hypotension, and leukopenia are adverse effects of the medication.
  9. Dantrolene
    • skeletal muscle relaxant and can cause liver damage; therefore, the nurse should monitor the results of liver function studies. They should be done before therapy starts and periodically throughout therapy.
    • Dantrolene is discontinued if no relief of spasticity is achieved in 6 weeks.

    Dantrium is hepatotoxic. The nurse observes for indications of liver dysfunction, which include jaundice, abdominal pain, and malaise. The nurse notifies the health care provider if these occur.
  10. Trihexyphenidyl is an anticholinergic medication
    used for the treatment of Parkinson's disease. Therefore, it can cause urinary hesitancy and retention, constipation, dry mouth, and decreased sweating.
  11. Magnesium citrate is available as an oral solution and should be served chilled to make it more palatable.
Card Set