Bio 93 Lecture 14

  1. At the end of each replication bubble is a
    replication fork
  2. What are helicases?
    enzymes that untwist the double helix at the replication forks
  3. What do single-strand proteins do?
    • binds to and stabilizes single stranded DNA until it can be used as a template
    • removes other proteins from DNA
  4. What do Topoisomerase do?
    corrects "overwinding" ahead of replication forks by breaking, swiveling, and rejoining DNA strands.
  5. What enzymes catalyze the elongation of new DNA at a replication fork?
    DNA polymerase
  6. Most DNA polymerases require a ____ and a template strand
    primer
  7. Which enzyme can start an RNA chain from scratch and adds RNA nucleotides one at a time using DNA as a template?
    primase
  8. The leading strand moves ____ the replication fork
    towards
  9. The leading strand is dependent on the actions of _____ _______
    DNA polymerase
  10. The lagging strand moves _____ from the replication fork
    away
  11. The lagging strand is synthesized as a series of fragments callled _____ ______
    Okazaki fragments
  12. Okazaki fragments are later joined by
    DNA ligase
  13. ____ ______ proofread newly made DNA, replacing any incorrect nucletides
    DNA polymerase
  14. Eukaryotic chromosomal DNA molecules have special nucleotide sequences at their ends called
    tolemeres
  15. Tolemeres _____ the erosion of genes near the ends of DNA molecules
    postpone
Author
jocelyn8
ID
336051
Card Set
Bio 93 Lecture 14
Description
DNA Replication and Repair
Updated