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Serological Problem Solving for Antibodies to high incidence antigens

Home Get App Take Quiz Create Clues in phenotypes Recently transfused? S-s- may be U- P1 may be P- or Vel- M-N- may be Ena- Negative for both common alleles may be have a null phenotype Group O may be H- Problem solving options Test selected cells negative for high incidence Ag's. Inhibition or neutralization studies Adsorption and elution to separate antibodies Chemical or enzyme treatments Clues in phenotypes Vel- are also sometimes P1- RBCs Ena- or MkMk phenotypes (which lack glycophorin A type as Wr(a-b-) Only positive with DTT/AET Bpa Ch/Rg Xg Negative for all chemicals & enzymes IN JMH Positive with DTT/AET & a-chymotrypsin M N ENaTS Ge2 &Ge4 Positive with DTT/AET & Trypsin *Variable with Ficin/papain S & s Positive with Trypsin Variable with DTT/AET YT Positive with DTT/AET, a-chymotrypsin, & trypsin EnaFS Positive with Ficin/papain Variable with DTT/AET LU MER2 Positive with Papain Variable with Ficin KN Positive with Ficin/Papain Weak with a-chymotrypsin DO Positive with Ficin/Papain, Trypsin Weak with DTT/AET CROM Positive with ficin/papain, trypsin, & DTT/AET Some DI Positive with ficin/papain, trypsin, & Pos or weak with a-chymotrypsin LW Positive with all  May be weak with Trypsin and a-chymotrypsin SC Positive with Trypsin, papain/ficin, a-chymotrypsin Kel *Except KALT which is destroyed by trypsin Positive for all ABO, AnWj, Sda ENaFR, U, P1PK, RH, LE, FY3, JK, most DI, CO, H, Ge3, OK, I/I, P, FORS, JR, LAN, CSa, ER, LKE, PX2, Vel, ABTI, Ata, EMM,  PEL,MAM Positive for all with * Enhanced activity with DTT/AET Kx Most common in whites k Era Lan Kpb Black common antibody marker U Jsb Joa Cra Esa Ata Japanese common antibody marker UMC Jra Oka Lan HTLA *Obsolete name* High Titer Low Avidity Antibodies Do not use HTLA anymore, however others may, so be familiar with those that have those characteristics Chido/Rodgers Knops Dombrock Cost John Milton Hagen

Author Kwalke12 ID 335869 Card Set Serological Problem Solving for Antibodies to high incidence antigens Description Serological Problem Solving for Antibodies to high incidence antigens Updated 2017-11-09T23:46:53Z Show Answers