Biochemistry Exam 1

Evidence that rRNA is essential for Protein Synthesis

Single cleavage in 16S rRNA could block translation

23S rRNA essential for peptide bond formation

Antibiotics interact with rRNA NOT protein
RNA Polymerase Functions
- Scans DNA for initiation sites
- Unwinds short stretches of DNA (~17 bp)
- Selects nucleotides
- Catalyzes phosphodiester bond formation (5'-->3') at +1
- Interacts with regualtory proteins to regulate transcription
What are the ways to alter genes available for Transcription?
- Methylation of DNA
- Gene amplification
- Gene rearrangement

Author

jdad

33509

Card Set

Biochemistry Exam 1

Description

Eukaryotic Gene Expression

Updated

2010-09-09T00:23:30Z

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