regulatory proteins that bind to the start of genes, either promoting or inhibiting the transcription of the gene
transcription factor
-example of transcription factor
-blocks tryptophan synthesis
escherichia coli
2 classes of genes that can have an effect on how other genes function
modifying genes
regulator genes
alter how certain other genes are expressed in the phenotype
modifying genes
can either initiate or block the expresion of other genes
regulator genes
regulator genes that are involved in subdividing an embryo into what will become the major body parts of an individual
homeotic genes
homeotic genes aka
homeobox
hox genes
defined by dna sequence of 180 nucleotides that code for a protein domain
homeotic genes
homeobox code for a protein domain called
homeodomain
their effect does not normally occur unless certain environment factors are present
incompletely penetrant
although genes contain all the information an organism uses to function,the environment plays an important role in determining the ultimate phenotype --- a dichtomy often referred to as
nature vs. nurture
during the process of DNA replication, errors occassionally occur in the polymerization of the second strand. these errors are called
mutations
(mutations) error rates are usually very low ____ - error in every 10-100 million bases due to _____________ ability of DNA polymerase
1
proofreading
processes that increases the rate of changes in DNA are called
mutagenoc
errors that create large structural changes in DNA sequence -- duplications, inversions, or deletions of entire regions, or ther accidental exchanging of whole parts between different chromosomes
translocation
chromosomal crossover aka
crossing over
the exchange of genetic material between homologous chromosomes during prophase 1 of meiosis
chromosomal crossover
the contact bet. two chromatids that will soon undergo crossing over is known as
chiasma
illustrated the crossing over (year 1916)
Thomas Hunt Morgan
______________ produce organisms with different genotypes, and those differences can result in different ___________
mutations
phenotypes
transmission of traits
multipple alleles
intermediate expression
codominance
epistasis
genes that have more than two alleles
multiple alleles
two alleles can be codominat
codominance
apparent blending can occur in the phenotype when there is incompatible dominance resulting in an ___________ of a trait in heterozygous individuals
intermediate expression
term applied when one gene interferes with the expression of another (eg: baldness/widow's peak)
epistasis
a pattern responsible for many features that seem simple on the surface
polygenic inheritance
polygenic inheritance is distinguished by
traits - quantified by measurement rather than counting
2 or more gene pairs contribute to the phenotype
phenotypic expression of polygenic traits varies over a wide range
an effect of a single gene on more than one characteristic