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Biochem Drugs/Proteins
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Rifampicin
Rifamycin
Inhibits initiation of RNA synthesis
Blocks formation of first phosphodiester bond
Actinomycin D
Inhibits RNA synthesis by incalating DNA
Causes mutations
Works in both pro- and eukaryotes
Alpha-amanitin
Inihibits eukaryotic RNA polymerase
RNA pol I - (nucleolus) insensitive
RNA pol II - (mRNA) highly sensitive
RNA pol III - (tRNA) moderately sensitive
Antibiotics to bacteria
Inhibit protein translation
Act of rRNA, not the ribosomal protein
Diphtheria toxin
Inihibits translocation of protein being synthesized
Puromycin
Causes premature chain termination
Acts like aminoacyl-tRNA
Affects both pro- and eukaryotes
Streptomycin
Inhibits initiation and causes misreading of mRNA in prokaryotes
Author
duncamunk
ID
33228
Card Set
Biochem Drugs/Proteins
Description
Drugs and developmental proteins covered on Test 1
Updated
2010-09-07T19:36:59Z
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