Final - Chapter 46/47 - Reproductive

  1. Plan B (levonorgestrel) must be taken when?
    • within 72 hours of unprotected sex
    • again 12 hours following first dose
  2. What are the common drug interactions of BCP?
    • antibiotics
    • antiepileptics
    • ↑ caffeine, corticosteroids, theophylline
    • ↓ warfarin, insulin
  3. what are the adverse effects of BCP (ethinyl estradiol with norethindrone)?
    • edema
    • nausea
    • abd cramps
    • dysmenorrhea, breakthrough bleeding
    • breast tenderness
    • fatigue
    • skin rash, acne
    • HA, weight gain
    • vaginal candidiasis
  4. What must a woman do if she skips a dose of BCP?
    Have backup birth control
  5. What is the action of depo-provera?
    inhibits the effect of estrogen on the uterus, restoring the normal hormonal balance
  6. How often is depo-provera given?
    IM every 3M
  7. what are the uses for depo-provera?
    • endometriosis
    • amenorrhea
    • uterine bleeding
    • contraception
  8. what are the SEVERE adverse effects of depo-provera?
    • BLACK BOX: when taken with estrogens
    • stroke
    • DVT
    • MI
    • pulmonary emboli
    • invasive breast CA
    • loss of bone density
  9. what are the adverse effects of depo-provera?
    • HTN
    • depression
    • +same as BCP
  10. what are the risks of HRT?
    • CAD
    • stroke
    • Breast CA
    • dementia
    • VTE (venous thromboembolism)
  11. what are the side effects of HRT?
    • increased skin pigmentation
    • weight gain
    • fluid retention
    • change in libido
    • breast tenderness
    • HA
    • moodiness
    • HTN
  12. what are the benefits of HRT?
    • ↓ menopausal symptoms
    • may prevent osteoporotic bone fx
  13. what is the mechanism of action of sildenafil (Viagra)?
    relaxes smooth muscle in corpus cavernosum - allows increased blood flow to penis
  14. what are the side effects of sildenafil (Viagra)?
    • hypotension
    • HA, dizziness, chest pain
    • flushing, rash
    • nasal congestion
    • UTI
    • dyspepsia, diarrhea
    • blurred vision, red eyes, changes in color perception
  15. what is the mechanism of action of alpha1 adrenergic blockers (cardura, hytrin, flomax) for BPH?
    inhibits constriction of smooth muscle cells to ease obstruction of urethra
  16. what are the side effects of alpha1 adrenergic blockers (cardura, hytrin, flomax) for BPH?
    • hypotension
    • dizziness
    • fatigue
    • HA
    • tachycardia
    • first dose phenomenon (severe hypotension, and syncope)
  17. what is the mechanism of action of finasteride (Proscar, Propecia) for BPH?
    • block enzyme in testosterone metabolic pathway
    • reduces size of prostate
  18. what are the side effects of finasteride (Proscar, Propecia) for BPH?
    • decreased libido
    • ED
    • depression
    • may take 6-12 months to work
    • teratogenic to male fetus
Author
cbennett
ID
331247
Card Set
Final - Chapter 46/47 - Reproductive
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Final - Chapter 46/47 - Reproductive
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