MCB

  1. Tight Junctions
    Seal gaps between epithelial cells via non-covalent bonds between homophillic adhesion proteins (claudins, occludins)
  2. Adherens Junction
    • Cell-cell anchoring junction that links epithelial cells together by binding to their actin filaments
    • Adhesion: Classical cadherins
    • Adaptor: A, B, Y, p120, vinculin
    • Filament: actin
  3. Desmosomes
    • Cell-cell anchoring junction that links epithelial cells together by binding to their intermediate filaments
    • Adhesion: Non-classical (Desmocollin, desmoglein)
    • Adaptor: Plakoglobin, plakophillin, desmoplakin
    • Filament: Intermediate
  4. Focal connections
    • Cell-matrix anchoring junctions that link epithelial cells to underlying ECM proteins of basal lamina by binding to actin filament
    • Adhesion: Dimeric integrin
    • Adaptor: Vinculin, talin
    • Filament: Actin
  5. Hemidesmosomes
    • Cell-matrix anchoring junctions that link epithelial cells to underlying ECM proteins by binding to intermediate filaments
    • Adhesion: dimeric integrins
    • Adaptor: plectin, dystonin
    • Filament: intermediate
Author
tori123
ID
331154
Card Set
MCB
Description
Hi
Updated