MBio - Metabolism II

Glycolytic pathways
- Embden-meyerhoff (Glycolysis) - Homo-
- Entner-douoroff (Glycolysis alternative)
- Pentose phosphate pathway
- Methylglyoxal pathway
Glycolysis net reaction
- Reactants: Glucose + 2ATP + 2Pi + 2NAD+
- Products: 2Pyruvate + 2ATP + 2 NADH + 2H2O
Entner Doudoroff net reaction
- Reactants: Glucose + ATP + Pi + + NADP⁺ + NAD+
- Products: 2Pyruvate + ATP + NADPH + NADH + H2O
- Lacks 6-phosphofructokinase
Pentose phosphate pathway
- Consumes 1 ATP to produce 5C sugars
- Complimentary to glycolysis-like pathways
- Erythrose 4-phosphate used in aromatic amino acids
- Heterofermentative or heterolactic
Methylglyoxal pathway
- Glycolysis alternative
- Consumes 2ATP to make pyruvate
Net reaction for the TCA cycle
- Reactants: pyruvate + FAD + 4 NAD+
- Products: 3CO2 + 4NADH + FADH2 + GTP
Uses of NADH and FADH2
- OxPhos
- Produce a proton gradient
- Used in chemiosmosis
Structure of ATPase
- F₀ - Multimeric transmembrane (proton channel)
- F₁ - Multimeric head, inside cell
Inhibitors
- Block ATPase activity
- CO, Cyanide
Uncouplers
- Uncouple proton movement from the ATPase
- Dinitrophenol
Energy products of aerobic respiration
- Glycolysis: 2ATP
- TCA cycle: 2 ATP (From GTP)
- OxPhos: 36-38 ATP (From e carriers)
Ethanolic fermentation (intermediates)
- Glycolysis -> Pyruvate -> Acetadehyde -> Ethanol
- Pyruvate decarboxylase

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Ant

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Card Set

MBio - Metabolism II

Description

MBio

Updated

2017-04-13T00:03:29Z

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