This antipsychotic is one of the first made, it is a strong sedative effect, decreases BP and has moderate EPS risk.
Chlorpromazine (thorazine)
What class is Fluphenazine (Prolixin)?
Antipsychotic
These two antipsychotic drugs have a low sedative effect, neutral action on BP, and strong risk of EPS.
Fluphenazine (Prolixin)
Perphenazine (Trilafon)
What class is Perphenazine (trilafon)?
Antipsychotic
Is Chlorpromazine typical or Atypical?
Typical
Is Fluphenazine typical or atypical?
typical
Is Perphenazine typical or atypical?
typical
What class is Haloperidol (Haldol)?
Antipsychotic
Is Haldol typical or atypical?
typical
This antipsychotic drug (typical) is the most widely used antipsychotic.
It is metabolized in the liver, and has multiple routes (PO, IV, IM)
It is scheduled and is long acting
Haldol
Is Loxapine typical or atypical?
typical
What class of drug is Loxapine (Loxitane)?
Antipsychotic
This antipsychotic is moderately sedating, strong risk of EPS, and HYPOtension is common.
Loxapine
Is Thiothixene (Navane) typiical or atypical?
typical
What class of drug is Thiothixene?
Antipsychotic
This antipsychotic s/e has low sedation and hypotension.
No EPS risk mentioned
Thiothixene
Typical antipsychotics will cause(some might be both):
1. Drowsiness or wakefullness
2. Hypotension or hypertension
3. Increased HR or decreased HR
4. Excess urination or urinary retention
5. Loose stools or constipation
1. Drowsiness
2. Both
3. Increased HR
4. Urinary retention
5. Constipation
T or F: typical antipsychotics can cause EPS
True
T or F: Atypical meds have a higher chance of EPS than typical
False
What is used to treat Dystonia?
It is relieved with anticholinergic meds and IM diphenhydramine (Benadryll) drugs
T or F: The side effect dystonia comes from typical antipsychotics
True
Akathisia is a side effect of __a___(typical/atypical) drugs and is treated with __b___.
a. Typical
b. Beta blockers or benzodiazepines
What is a rare and potentially fatal side effect of antipsychotic medications?
NMS (Neuroleptic Malingnant Syndrome)
List symptoms of NMS
muscle rigidity
sudden high fever (up to 105)
altered LOC
fluctuations in BP
tachycardia
dysrhythmias
seizures
rhabdomyolysis
ARF
respiratory failure
coma
death
List 4 interventions to treat NMS
1. Immediate withdrawal of antipsychotic medication
2. IV fluids to hydrate
3. Hypothermia blankets
4. administration of antipyretics, benzodiazepines, muscle relaxants
What class and generation of drug can cause blood dyscrasias (agranulocytosis)?
Typical antipsychotics
T or F: Typical antipsychotics might cause strong photosensitivity
True
Could Typical antipsychotics lower or raise seizure threshold?
Lower
A patient who is taking a typical antipsychotics reports his urine is a brown color. Does this require immediate intervention?
No, this is considered harmless.
Metabolites can cause the urine to turn a pinkish to brown color
How long does it take to see therapeutic effects of typical antipsychotic drugs?
3-6 weeks
Some possible improvement as early as 7-10 days
What is the most common side effect for typical antipsychotic medications?
Pseudoparkinsonism
If EPS is to develop in a patient taking typical antipsychotic drugs, how soon will symptoms show themselves?
5-30 days after the start of medication
Antiarkinson / Anticholinergic drugs are given to block which NT in the CNS and PNS?
Acetylcholine
What do these phrases mean in terms of side effects of anticholinergics?
1. "hot as a hare"
2. "blind as a bat"
3. "dry as a bone"
4. "red as a beet"
5. "mad as a hen"
1. fever
2. blurred vision
3. dry mouth
4. hot/dry skin
5.
T or F: anticholinergic can decrease sweat production
True
T or F: anticholinergic can cause decreased GI function
true: decrease gut motility and urinary retention as well
T or F: Typical antipsychotics are not as likely to cause EPS or tardive dyskinesia compared to atypical drugs
False
Why is diabetes an increased risk for patients taking atypical antipsychotics?
Due to increased hunger and altered carbohydrate metabolism in atypical drugs
T or F: when taking atypical antipsychotics, you want to avoid direct sunlight
true
Why can smoking be harmful for a patient taking atypical antipsychotics?
smoking increases metabolism of antipsychotic medications
What class of drug is Clozapine (Clozaril)?
Antipsychotic (atypical)
Is Clozapine typical or atypical?
Antipsychotic (atypical)
What class of drug is Rsperidone (risperdal)?
Antipsychotic (atypical)
Is Risperidone typical or atypical?
Antipsychotic (atypical)
What class of drug is Olanzepine (Zyprexa)?
Antipsychotic (atypical)
Is olanzepine typical or atypical?
Antipsychotic (atypical)
What class of drug is Quetiapine (Seroquel)?
Antipsychotic (atypical)
Is Quietiapine typical or atypical?
Antipsychotic (atypical)
What class of drug is Paliperidone (Invega)?
Antipsychotic (atypical)
Is Invega typical or atypical?
Antipsychotic (atypical)
What class of drug is Lurasidone (Latuda)?
Antipsychotic (atypical)
Is Lurasidone (Latuda) typical or atypical?
Antipsychotic (atypical)
What class of drug is Ziprasidone HCL (Geodon)?
Antipsychotic (atypical)
What class of drug is Aripiprazole (Abilify)?
Antipsychotic (atypical)
How often does a patient taking atypical antipsychotics need to monitor lab work?
Q3Months
Pinkish to brown discoloration of urine can occur in ____ (typical/atypical) antipsychotics
typical
Which antipsychotic will you monitor someone's WBC?
Clozaril
What are the 3 common anthicholinergics?
Diphenhydramine, Benztropine, Trihexyphenidyl HCl
Weight gain can occur with ____ typical/atypical antipsychotics
atypical
This atypical antipsychotic can cause major weight gain.
Olanzepine (Zyprexa)
What special consideration for Ziprasidone HCL (Geodon)?
monitor heart EKG
Which class of drug can cause DM, Hyperlipidemia and CAD?
Atypical Antipsychotics
What are the two most common Benzodiazepines?
Lorazepam (ativan)
Clonazepam (Klonopin)
T or F: antidepressants can also be used to treat anxiety
True
Which 3 antidepresssants are used to treat anxiety?
