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Buspirone
- "BuSpar" ~ antianxiety
- Used for Panic disorder, social anxiety disorder, Obsessive-compulsive, and trauma stress disorders such as PTSD
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Adverse effects of buspirone
- dizziness
- nausea
- HA
- lightheadedness
- agitation
- *advise to take food to reduce nausea
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Contraindications/precautions with buspirone
- Preg risk Category B
- Not recommended during breastfeeding
- Use with caution in older adults and pt's with liver and renal dysfunction
- Can't use with MAOI due to hypertensive crisis
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Lorazepam
- "Ativan" ~ is a benzodiazepine
- Relief of anxiety occurs rapidly following administration
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Therapeutic uses for Lorazepam
- Generalized anxiety disorder and panic disorder
- Other uses:
- seizure disorders
- insomnia
- muscle spasm
- alcohol withdrawl
- induction of anestesia
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Adverse effects of Lorazepam (benzo's)
- CNS depression (sedation, etc.)
- Anterograde amnesia (difficulty recalling)
- Paradoxical response (insomnia, excitation, euphoria, rage)
- Manifestations of withdrawal include anxiety, insomnia, diaphoresis, tremors
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Contraindications/Precautions of Lorazepam
- Preg risk Cat D
- Contraindicated in pt w sleep apnea, respiratory depression, and/or glaucoma
- Use cautiously in pt's with liver disease or hx of mental illness or substance abuse
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Theophylline
- Med for respiratory system
- causes bronchodilation
- Long term control of asthma and COPD
- Once first-line med for asthma, now used infrequently cause newer meds are safer and more effective
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Theophylline toxicity
- Monitor serum levels to keep within therapeutic ranges (5-15 mcg/mL)
- Adverse effects are unlikely to occur at less than 20 mcg/mL
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