The anticoagulant of choice for most routine coagulation studies is:
A) Sodium citrate
If a clot is incubated at 37 degrees C. and dissolves within 24 hours, which of the following should be suspected?
D) fibrinolysins
Coagulation factors affected by coumarin drugs are:
D) II, VII, IX, and X
Which one of the following statements concerning vitamin K is NOT true?
A) Heparin inhibits the action of vitamin K
The following data were obtained on a patient: PT 20 seconds, APTT 55 seconds, APTT plus aged serum corrected. APTT plus adsorbed plasma not corrected. Circulatory inhibitor not present. Which of the following coagulation factors is deficient?
C) Factor X
A coagulation factor synthesized in the liver and vitamin K dependent is:
A) prothrombin
When performing platelet aggregation studies which set of platelet aggregation responses would most likely occur in a patient with Bernard Soulier syndrome?
C) Normal platelet aggregation to collagen, ADP and epinephrine; decreased to ristocetin
Which of the following is most commonly associated with activated protein C resistance (APCR)?
B) thrombosis
Factor XII deficiency is associated with:
C) Increased risk of thrombosis.
The following factors are measured by either the PT or the aPTT except:
B) Factor XIII
A modification of which procedure can be used to quantitatively measure fibrinogen?
A) Thrombin Time
Aspirin prevents platelet aggregation by inhibiting the action of which enzyme?
D) cyclooxygenase
which test results is anticipated to be normal in a patient with dysfibrinogenemia
D) Immunologic fibrinogen level
When a sample has been flagged as being icteric by an automated coagulation analyzed, which of the following methodologies would be most susceptible to erroneous results due to the interfering substance?
A) Photo-optical clot detection
Which ratio of anticoagulant to blood is correct for coagulation procedures?
D) 1:9
What adjustments should be made when a patient with polycythemia vera is drawn for coagulation studies
B) Plasma should be drawn into a syringe with less citrate than the whole blood volume would ordinarily require.
What reagents are used in the PT test?
B) Thromboplastin and calcium
Which test would be abnormal in a patient with factor IX deficiency?
B) APTT only
Which test would be abnormal in a patient taking excess amount of coumadin?
D) PT only
Which clotting factor is not measured by PT and APTT tests?
C) Factor XIII
Which of the following can be modified to quantitatively measure fibrinogen levels?
B) Thrombin time
Which coagulation tests would be abnormal in a vitamin K deficient patient?
D) PT and APTT
Which of the following is referred to as an endogenous activator of plasminogen?
B) Tissue plasminogen activator
A standard 4.5 ml blue top tube is filled with 3.0ml of blood and submitted for PT and APTT tests. The sample is from a patient undergoing surgery the following morning for a tonsillectomy. Which of the following is the necessary course of action by the CLS?
A) Reject the sample and request a new sample
Which of the following statements is correct regarding sample storage for the prothrombin time test?
D) Stable for 24 hours if the sample is capped
Normal platelet adhesion depends on:
B) Glycoprotein Ib
Bernard Soulier syndrome is associated with:
D) Thrombocytopenia and giant platelets
Which of the following is characteristic of acute idiopathic thrombocytopenic purpura?
A) Spontaneous remission within a few weeks
Storage pool deficiencies are defects of:
C) Platelet granules
Which defect characterizes Gray Platelet syndrome?
