-
glimepiride
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Amaryl
- 2. 2nd generation sulfonylurea
- 3. Type II Diabetes Mellitus
- 4. inhibit ATP-K+ channels in pancreas, causing Ca2+ channel activation/influx that releases insulin
- 5. 1-2 mg once daily; 8mg per day, max dose
- 6. ACEi, Beta- Blockers, Fluoroquinolones
-
glipizide IR, ER
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Glucotrol, Glucotrol XL
- 2. 2nd generation sulfonylurea
- 3. Type 2 Diabetes Mellitus
- 4. Therapeutics II Top 200 - Endocrinology Cardiovascular_Renal Dermatology Respiratory
- 5. 5 mg po qd before breakfast
- 6. ACEi, Beta- Blockers, Fluoroquinolones
-
glyburide IR
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Diabeta
- 2. 2nd generation sulfonylurea
- 3. Type 2 Diabetes Mellitus
- 4. inhibit ATP-K+ channels in pancreas, causing Ca2+ channel activation/influx that releases insulin
- 5. initial 2.5 mg to 5 mg po qd, or 2 divided doses; max 5 mg/day. Maintenance 1.5 to 20 mg; Max 20 mg/day
- 6. BEERS List; ACEi, Beta- Blockers, Fluoroquinolones
-
insulin glargine
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Lantus
- 2. antidiabetic
- 3. Type 1 & 2 Diabetes Mellitus
- 4. Regulates glucose metabolism; stimulates glucose uptake my muscles and fat; inhibits lipolysis and proteolysis; enhances protein synthesis
- 5. Type 1: initial 1/3 of total daily dose QD then titrate to glucose reading; Type 2: 10 units QD (0.2 units/kg) then titrate to glucose reading
- 6.
-
levothyroxine
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Synthroid
- 2. thyroid function
- 3. Hypothyroidsim
- 4. Synthetic T4 (thyroxine) is converted to active T3 stimulate thyroid receptors in cell nucleus
- 5. In otherwise healthy, 1.7 mcg/kg/day (100 - 125 mcg for 70kg adult); w/ cardiac disease, 25 - 50 mcg; elderly w/ cardiac disease, 12.5 - 25 mcg/day and increase until TSH normalizes; in severe hypothyroidsm, 12.5 to 25 mcg/day until TSH normalizes
- 6. Black Box: Not used for weight loss, severe toxicity
-
metformin IR, ER
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Glucophage, Glucophage XR
- 2. biguanide
- 3. Type 2 Diabetes Mellitus; Polycystic Ovary Syndrome
- 4.
- 5.
- 6.
-
phentermine
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Adipex-P, Lomaira
- 2. antiobesity agent
- 3. Obesity
- 4.
- 5.
- 6.
-
sitagliptan
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Januvia
- 2. Dipeptidyl Peptidase V inhibitor
- 3. Type 2 Diabetes Mellitus
- 4.
- 5.
- 6.
-
amlodipine
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Norvasc
- 2. antihypertensive
- 3. HTN, stable angina, Reynaud's, Silent MI
- 4.
- 5.
- 6.
-
amlodipine/benazepril
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Lotrel
- 2. ACEi/Calcium channel blocker
- 3. HTN
- 4.
- 5.
- 6.
-
aspirin
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Ecotrin
- 2. NSAID, Salicylate
- 3. Fever, headache, Migraine, Pain, Afib, MI, Thromboembolism
- 4.
- 5.
- 6.
-
atenolol
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Tenormin
- 2. Beta-blocker 1 selective, antihypertensive
- 3. HTN, Afib (Rate control)
- 4.
- 5.
- 6.
-
atorvastatin
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Lipitor
- 2. antilipemic, HMG-CoA Reductase inhibitor
- 3. Hyperlipidemia, Hypercholesteremia
- 4.
- 5.
- 6.
-
benazepril
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Lotensin
- 2. ACE inhibitor, antihypertensive
- 3. HTN
- 4.
- 5.
- 6.
-
carvedilol IR
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Coreg
- 2. Non-selective beta blocker w/ alpha 1 activity
- 3. HTN, HF, LV following MI, Afib (Rate control)
- 4.
- 5.
- 6.
-
clonidine
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Catapres
- 2. alpha-2 adrenergic agonist, antihypertensive
- 3. HTN, opioid withdrawal
- 4.
- 5.
- 6.
-
clopidogrel
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Plavix
- 2. Thienopyradine, Antiplatelet
- 3. ACS, CAD, Afib, CABG
- 4.
- 5.
- 6.
-
diltiazem
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Cardizem
- 2. Non-dihydropyradine calcium channel blocker
- 3. Angina, HTN, Afin/Aflutter (rate control), SVT
- 4.
- 5.
- 6.
-
enalapril
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Vasotec
- 2. ACE inhibitor, antihypertensive
- 3. HTN, HF, asymptomatic LV
- 4.
- 5.
- 6.
-
enoxaparin
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Lovenox
- 2. Low Molecular Weight Heparin, Anticoagulant
- 3. DVT, STEMI, Unstable angina (NSTEMI)
- 4.
- 5.
- 6.
-
ezetimibe
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Zetia
- 2. Antilipemic agent
- 3. Homozygous Familial Hypercholesteremia, Primary Hyperlipidemia
- 4.
- 5.
- 6.
-
fenofibrate/fenofibric acid
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Tricor
- 2. Antilipemic Agent, Fibric Acid
- 3. Hypertriglyceridemia, Hyperlipidemia, Hypercholesteremia
- 4.
- 5.
- 6.
-
folic acid
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Apo-folic
- 2. Vitamin
- 3. Megaloblastic Anemia, neural tube defects
- 4.
- 5.
- 6.
-
furosemide
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Lasix
- 2. Loop diuretic, antihypertensive
- 3. Edema/HF, Acute Pulmonary Edema, Ascites
- 4.
- 5.
- 6.
-
heparin
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Unfractionated Heparin
- 2. Anticoagulant
- 3. ACS, Afib, Venous thromboembolism, thromboprophylaxis
- 4.
- 5.
- 6.
-
hydralazine
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Apresoline
- 2. Vasodilator
- 3. HTN, HF
- 4.
- 5.
- 6.
-
hydrochlorothiazide
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Microzide
- 2. Diuretic, thiazide
- 3. Edema, HTN
- 4.
- 5.
- 6.
-
isosorbide mononitrate
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Imdur
- 2. Vasodilator
- 3. Angina pectoris
- 4.
- 5.
- 6.
-
lisinopril
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Prinivil, Zestril
- 2. ACE inhibitor
- 3. Acute MI, HF, HTN
- 4.
- 5.
- 6.
-
lisinopril/hydrochlorothiazide
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Zestoretic
- 2. ACE inhibitor/Thiazide Diuretic
- 3. HTN
- 4.
- 5.
- 6.
-
losartan
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Cozaar
- 2. ARB, antihypertensive
- 3. HTN, Diabtetic neuropathy, HTN- w/ LV dysfunction, HF
- 4.
- 5.
- 6.
-
losartan/hydrochlorothiazide
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Hyzaar
- 2. ARB/Thiazide Diuretic
- 3. HTN, HTN- w/ LV hypertrophy
- 4.
- 5.
- 6.
-
lovastatin
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Mevacor
- 2. Antilipemic agent, HMG-CoA reductase inhibitor
- 3. Dyslipidemia, primary prevention of CAD and ASCVD
- 4.
- 5.
- 6.
-
metoprolol succinate
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Toprol XL
- 2. Beta blocker 1 selective, antihypertensive, antianginal agent
- 3. Angina, Afib/flutter (ventricular rate control), HF, HTN, MI, SVT
- 4.
- 5.
- 6.
-
metoprolol tartrate
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Lopressor
- 2. Beta blocker 1 selective, antihypertensive, antianginal agent
- 3. Angina, Afib/flutter (ventricular rate control), HF, HTN, MI, SVT
- 4.
- 5.
- 6.
-
nebivolol
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Bystolic
- 2. Beta blocker 1 selective
- 3. HTN, CABG, Ischemic Heart Disease, Valvular Heart Disease
- 4.
- 5.
- 6.
-
potassium chloride
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Klor-Con
- 2. Electrolyte Supplement
- 3. Hypokalemia
- 4.
- 5.
- 6.
-
pravastatin
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Pravachol
- 2. Anti Lipemic Agent, HMG-CoA Reductase Inhibitor
- 3. Hyperlipidemia, prevention of primary and secondary cardiac events
- 4.
- 5.
- 6.
-
propranolol LA/XL
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Inderal LA, Inderal XL
- 2. Beta Blocker Non-Selective, Antiarrhythmic, Antianginal agent
- 3.
- 4.
- 5.
- 6.
-
ramipril
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Altace
- 2. ACE inhibitor, Antihypertensive
- 3. HF, HTN, reduction of MI/Stroke
- 4.
- 5.
- 6.
-
rivaroxaban
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Xarelto
- 2. Factor Xa Inhibitor, Anticoagulant
- 3. DVT, reduction of risk of DVT/PE
- 4.
- 5.
- 6.
-
rosuvastatin
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Crestor
- 2. HMG-CoA Reductase Inhibitor, Anti Lipemic Agent
- 3. Hyperlipidemia, Hypertriglyceridemia, Homozygous familial hypercholesterolemia
- 4.
- 5.
- 6.
-
simvastatin
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Zocor
- 2. HMG-CoA Reductase Inhibitor, Anti Lipemic Agent
- 3. Homozygous Familial Cholesteremia, Hyperlipidemia
- 4.
- 5.
- 6.
-
spironolactone
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Aldactone
- 2. K+ sparing Loop Diuretic
- 3. Edema, hypokalemia, HF, diagnosis of primary alodsteronism, Hirsutism in women (off-label)
- 4.
- 5.
- 6.
-
triamterene/hydrochlorothiazide
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Maxzide
- 2. Antihypertensive, Potassium sparing thiazide diuretic
- 3. HTN, Edema
- 4.
- 5.
- 6.
-
valsartan
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Diovan
- 2. ARB, Antihypertensive
- 3. HTN, HF, LV dysfunction or MI
- 4.
- 5.
- 6.
-
valsartan/HCTZ
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Diovan HCT
- 2. ARB, Diuretic Thiazide, Antihypertensive
- 3. HTN
- 4.
- 5.
- 6.
-
warfarin
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Coumadin
- 2. Vitamin K Antagonist, Anticoagulant
- 3. Thromboembolism, MI
- 4.
- 5.
- 6.
-
albuterol HFA
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Pro-Air, Proventil, Ventolin
- 2. Beta 2 Agonist, Bronchodilator
- 3. Asthma, Bronchospasm, COPD, Hyperkalemia (off label)
- 4.
- 5.
- 6.
-
benzonatate
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Tessalon Perles
- 2. Antitussive
- 3. Cough
- 4.
- 5.
- 6.
-
cetirizine
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Zyrtec
- 2. 2nd gen. Histamine H1 Antagonist
- 3. Upper respiratory allergies, Urticaria,
- 4.
- 5.
- 6.
-
dextromethorphan
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1.
- 2. Delsym
- 3. Antitussive, N-Methyl-D-Aspartate Receptor Agonist
- 4.
- 5.
- 6.
-
diphenhydramine
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Benadryl
- 2. 1st gen. Histamine H1 Antagonist
- 3. Allergic reactions, Antitussive, Motion Sickness, Occasional, Insomnia, Parkinsonism, Rhinitis- sneezing due to cold, Anaphylaxis (adjunct to epinephrine - off label)
- 4.
- 5.
- 6.
-
fluticasone HFA
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Flovent
- 2. Corticosteroid
- 3. Asthma
- 4.
- 5.
- 6.
-
fluticasone propionate
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Flonase Allergy Relief
- 2. Corticosteroid
- 3. Non-Allergic Rhinitis, upper respiratory allergies
- 4.
- 5.
- 6.
-
fluticasone/salmeterol Diskus
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Advair Diskus, Advair HFA
- 2. Beta 2 Adrenergic Agonist, Long Acting, Corticosteroid
- 3.
- 4.
- 5.
- 6.
-
formoterol/budesonide
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Symbicort
- 2. Beta 2 Adrenergic Agonist, Long Acting
- 3. Asthma, COPD
- 4.
- 5.
- 6.
-
guaifensen IR, ER
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Mucinex
- 2. Expectorant
- 3. Cough (expectorant)
- 4.
- 5.
- 6.
-
ketotifen
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Alaway, Zaditor
- 2. 2nd gen. Histamine H1 Antagonist, Mast Cell Stabilizer
- 3. Allergic conjunctivitis
- 4.
- 5.
- 6.
-
loratadine
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Claritin
- 2. 2nd gen. Histamine H1 antagonist
- 3. Seasonal Allergic Rhinitis, Urticaria
- 4.
- 5.
- 6.
-
mometasone
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Nasonex
- 2. Corticosteroid
- 3. Allergic Rhinitis, Nasal Congestion, Nasal Polyps
- 4.
- 5.
- 6.
-
montelukast
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Singulair
- 2. Leukotriene Receptor Antagonist
- 3. Allergic Rhinitis, Asthma, Bronchoconstriction, Chronic Urticaria and NSIAD induced Urticaria (off label)
- 4.
- 5.
- 6.
-
oxymetazoline
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Vicks Sinex 12HR Decongestant, Afrin 12HR
- 2. Adrenergic Agonist, Decongestant
- 3. Nasal Congestion
- 4.
- 5.
- 6.
-
phenylephrine
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Non-Pseudo Sinus Decongestant, Sudafed PE Children's
- 2. Alpha Adrenergic Agonist
- 3. HYPO-tension/Shock, Nasal congestion, Priaprism (off label)
- 4.
- 5.
- 6.
-
pseudoephedrine
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Sudafed
- 2. Alpha/Beta Agonist, Decongestant
- 3. Nasal Congestion
- 4.
- 5.
- 6.
-
tiotropium Handihaler
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Spiriva HandiHaler
- 2. Anticholinergic Agent, Long Acting
- 3. COPD
- 4.
- 5.
- 6.
-
triamcinolone nasal
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Nasacort Allergy 24HR
- 2. Corticosteroid
- 3. Allergic Rhinitis/upper respiratory symptoms, Acute Bacterial Rhinosinusitis, adjunct to antibiotics (empiric treatment)
- 4.
- 5.
- 6.
-
clobetasol
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Cormax, Temovate, Embeline
- 2. Anti-inflammatory Agent
- 3. Psoriasis, steroid responsive dermatoses
- 4.
- 5.
- 6.
-
hydrocortisone topical
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Aquanil, Cortaid (and many more)
- 2. Corticosteroid, Antihemorrhoidal Agent
- 3. Dermatoses, Atopic Dermatitis, Anal and Genital itching
- 4.
- 5.
- 6.
-
hydroxyzine HCl
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Vistaril
- 2. Antiemetic, 1st gen. Histamine H1 Antagonist
- 3. N/V, Anxiety, Pruritis
- 4.
- 5.
- 6.
-
miconazole topical
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Lotrimin, Vagistat
- 2. Antifungal Agent
- 3. Tinea-pedis, -corporis, -cruris, and Vulvovaginal candiasis
- 4.
- 5.
- 6.
-
nystatin topical
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Nystop, Nyamyc
- 2. Antifungal Agent
- 3. Fungal infections (cutaneous and mucocutyaneous)
- 4.
- 5.
- 6.
-
terbinafine topical
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Lamisil
- 2. Antifungal Agent
- 3. Tinea-pedis, -corporis, -cruris, -versicolor, and Cutaneous candiasis
- 4.
- 5.
- 6.
-
triamcinolone topical
1. Brand
2. Class
3. Indication
4. MOA
5. Dose
6. ADR/ADE/Major DDI
- 1. Kenalog, Oralone, Triderm
- 2. corticosteroid
- 3. Dermatoses, ulcerative lesions
- 4.
- 5.
- 6.
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