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Unicellular organisms use ____ ____ primarily for reproduction. Multicellular organisms use the same process for _____ & _____ of tissues
- cell divison
- growth & repair of tissues
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Four events that must occur for cell division:
- Reproductive signal (initiate cell div.)
- replication (of DNA)
- segregation (distrib. of DNA into 2 cells)
- cytokinesis (cleaving of those cells into separates)
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In eukaryotes, signals for cell division are related to the _____ of the entire organism. Eukaryotes usually have many ______; the process of replication & segregation are more _______
- needs
- chromosomes
- intricate
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DNA replication usually occurs between ___ ____. ____ ____ are newly replicated chromosomes that are genetically identical. _____ separates them into two new nuclei identical to the parent cell.
- cell divisions
- Sister chromatids
- Mitosis
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Meiosis is the _____ ____ in cells involved in ______ _______. The cells resulting from meiosis are not ______ to the parent cells
- nuclear division
- sexual reproduction
- identical
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The cell cycle is the period between cell divisions divided into _____/______ and ______.
- mitosis/cytokinesis
- interphase
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Interphase is when the ______ _____ is visible and cell functions like _____ occur. Interphase begins after _______ and ends when _____ starts
- cell nucleus
- replication
- cytokinesis
- mitosis
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Interphase has three subphases name them.
G1, S phase and G2
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G1 occurs between the end of ______ and onset of ______; chromosomes are
_____, ______ structures
- cytokinesis
- S phase
- single & unreplicated
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In S phase, the DNA ______; one chromosome becomes two ____ ______. Gap 2 occurs at the end of ______, cell prepares for _____. In M phase, _____ & ____ occur
- replicates
- sister chromatids
- S phase
- mitosis
- mitosis & cytokinesis
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Growth factors are ______ chemical signals that stimulate cells to divide. Some white blood cells produce _______ that promote cell division in other white cells
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Erythropoietin produced in the ______ stimulates division of _____ ____ cells and production of ____ ___ cells
- kidneys
- bone marrow cells
- red blood cells
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After DNA replicates, its segregation occurs during _______. The DNA molecules is complexed with proteins to form dense ______. ______ coat DNA to make it compact at the end of G2. Sister chromatids are held together by _____ which is removed during mitosis except at the ______.
- mitosis
- chromatin
- Condensins
- cohesin
- centromere
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DNA molecules are extensively packed even during the ______. Packing is achieved by ________, proteins with positive charges that attract negative _____ groups of DNA. Interactions result in the formation of beadklike units or _______
- interphase
- histones
- phosphate
- nucleosomes
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The ________ determines the plane of cell division. It doubles during the S phase and will determine the _______ orientation. Each centrosome can consist of ___ ____
- centrosome
- spindle
- two centrioles
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Centiroles
hollow tubes formed by microtubules at right angles
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The centrosomes move to opposite ends of the nuclear envelope during ____-to-_____ transition. Orientation determines the plane at which the cell will _____ and the ______ relationship between them.
- G2-to-M transition
- divide
- spatial
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The phases of mitosis (5)
- Prophase
- Prometaphase
- Metaphase
- Anaphase
- Telophase
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During the propahase ______ disappears except at the centromere and chromatids become ______. ______, for movement, develop in the centromere regions. Centrosomes serve as _____ _____ or _____; microtubules from between the poles to make the ______.
- cohesin
- visible
- Kinetochores
- mitotic centers or poles
- spindle
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Kinetochore microtubules attach to kinetochores on the ______. Sister chromatids attach to opposite halves of the _____.
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During ______ the nuclear envelope breaks down. Chromosomes consisting of two chromatids attach to the ______ _____
- prometaphase
- kinetochore microtubules
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During metaphase
chromosomes line up at the midline of the cell
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Anaphase is the separation of the _____ _____. After separation they move to opposite ends of the spindle and are referred to as _____ ______
- sister chromatids
- daughter chromosomes
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Telophase occurs after chromosomes have _______. During telophase ______ breaks down, ______ uncoils, the _____ & _____ appear and two ____ nuclei are formed with identical genetic info
- separated
- spindle
- chromosome
- nuclear envelope & nucleoli
- daughter
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Cytokinesis is the _____ of the cytoplasm, differs in plants and animals. Animal cells' plasma membrane pinches between the ______ because of the _____ ring of microfilaments of ____ & _____
- division
- nuclei
- contractile ring
- actin & myosin
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Sexual reproduction involves the production of offspring that are ______ to the parents. It requires _______ created by meiosis; two parents contribute one _______ to an offspring.
- not identical
- gametes
- gamete
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Gametes contain only one set of _______. Haploid is the number of _______ (1n). Fertilization is when the two _____ gametes fuse to form a _____ zygote
- chromosomes
- chromosomes
- haploid
- diploid (2n)
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Diplontic life cycle is noted in some plants and and animals, gametes are the only ______ stage. The mature organism is ______ and produces gametes by ______. Gametes fuse to form diploid _____ which divides by _____ to form mature organism
- haploid stage
- diploid
- meiosis
- zygote
- mitosis
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Sexual reproduction generates _____ among individual organisms. It allows the random selection of _____ the diploid chromosome set, which forms a haploid gamete that fuses with another to make a _____ cell. Thus, no two individuals have ____ ____ makeup
- diversity
- half
- diploid
- identical genetic
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Meiosis consists of two nuclear divisions but DNA is replicated ____. The function of meiosis is to: (3)
once
- Reduce the chromosome number from diploid to haploid
- Ensure that each haploid has a complete set of chromosomes
- Generate diversity among the products
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During prophase I, the homolgous chromosomes pair via ______. The four chromatids of each homologous pair form a _____ or a ______
- synapsis
- tetrad (bivalent)
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Prophase I and metaphase I: the _____ continues to coil and compact. The homologs seem to _____ each other but are held together at the _______ that form between _______ chromatids
- chromatin
- repel
- chiasmata
- non-sister chromatids
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Exchange of genetic material occurs at the ______ during meiosis (prohase I & metaphase I), this is called _____ _____. ____ ____ results in _______ chromatids and increases genetic diversity of the products
- chiasmata
- crossing over
- recombinant chromatids
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Where are chromosomes during Metaphase I? What holds together homologous pairs?
- equatorial plate
- chiasmata
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During anaphase I, _______ chromosomes separate; ______ nuclei contain only one set of chromosomes. Each chromosome consists of two _______.
- homologous
- daughter nuclei
- chromatids
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In Meiosis I maternal chromosomes pair with paternal ______ during _____. This does not occur during _____. Crossing over is one reason for genetic diversity, it results in _______ _______ during anaphase I (good for chance combinations)
- homologs
- synapsis
- mitosis
- independent assortment
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Telophase I involves the reaggregation of the _____ _____ and then an interphase called _______. In some organisms, ______ begins immediately
- nuclear envelope
- interkinesis
- meiosis II
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Differences between meiosis II and mitosis (3)
- DNA does not replicate before meiosis II
- In meiosis II the sister chromatids may not be identical because of crossing over
- The number of chromosomes at the equatorial plate in meiosis II is half the number of those in mitosis
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