Excretory systems control ______, ______ and ______ of the ______ fluid and excrete _____. Cell volume depends on water movement to or from ______ _____. Water movement depends on differences in _____ ______.
volume, concentration and composition
extracellular
waste
extracellular fluid
solute concentrations
The osmolarity of a solution is the number of moles of active _____ per liter of _____. The osmolarity of the extracellular fluid must be maintained for _____ _____ balance.
solute per liter of solvent
cellular water balance
Excretory organs control ______ & ______ of extracellular fluids
osmolarity & volume
How do excretory organs control osmolarity and volume of extracellular fluids
excreting excess solutes (NaCl)
conserving rare or valuable solutes (glucose)
_____ is the output of the excretory system. Name the three processes excretory systems have in common
Filtration—extracellular fluid is filtered to contain no cells or large molecules
Secretion—modifies the filtrate
Reabsorption—concentrates the urine
Animals in different environments have diff. excretory functions. The difference between terrestrial animals and freshwater animals is that terrestrial animals must conserve ____ & ____ while freshwater animals must conserve _____ and ____ ____ ____.
salts and water
conserve salts and excrete excess water
Animals must eliminate metabolic waste product. For instance, carbs and fats end as ____ & ____ and are easily _____. Proteins and nucleic acids contain ______ so metabolism produces ______ ______.
water & CO2
excreted
nitrogen
nitrogenous waste
Most species secrete more than one nitrogenous waste. Human are _____ meaning they primarily excrete _____. However, we also excrete _____ ____ and ______
Ureotelic
urea
uric acid
ammonia
Uric acid is from the metabolism of _____ ____ and _____. Ammonia regulates _____ of extracellular fluid by buffering ____.
nucleic acids & caffeine
pH
urine
Vertebrates are well adapted to excrete excess water. The ______ is the main excretory organ and the nephron is the ____ _____ ____ of the _____. Nephrons filter large volumes of ____ and achieve bulk _______.
kidney
main functional unit of the kidney
blood
reabsorption
Ureters are _____ from the kidney that leads to the ______ _____. While the urethra is a tube for urine _______ leading from the urinary bladder where urine is _____ to the world
ducts
urinary bladder
excretion
stored
Urine formation in vertebrate nephrons involves what three processes
filtration
tubular reabsorption
tubular secretion
Blood is filtered in the _______, a ball of capillaries. ______ filtrate flows into the _______ tubule where it is modified by reabsorption of _____ _____, ______ and _____.
glomerulus
glomerular filtrate
renal tubule
specific ions, nutrients and water
True or false... further modifications occur in the renal tubules
true
Blood enters the glomerulus through the _____ _____ and leaves through the ______ ______. The ______ _____ feeds the peritubular capillaries, which surround the tubule and serve as _____ _____
afferent arteriole
efferent arteriole
efferent arteriole
exchange sites
The renal tubule begins with ______ ______ which encloses the glomerulus. ______ are capsule cells that contact the glomerular capillaries and have fine processes that wrap around the capillaries like feet.
bowman's capsule
podocytes
What keeps the rate of filtration high in the glomerulus? (2)
High capillary blood pressure
High permeability of glomerular capillaries and their podocytes
_______ are membrane proteins abundant in highly water-permeable areas such as _____ ______ _____ and ______ ______ of ______. They are absent from _____ _____ of _____
Aquaporins
Proximal convoluted tubule
descending loops of Henle
ascending loops of Henle
The proximal convoluted tubule (PCT) is responsible for the _____ ______ of water and solutes. Basically keeps the osmolarity _______.
isosmotic reabsorption
constant
How does the PCT keep osmolarity constant? (3)
PCT cells have microvilli to increase surface area, and have mitochondria
They actively transport Na+, glucose, and amino acids
Water follows the transport of solutes
Concentration of urine is due to a ________ _______ mechanism in the loops of Henle. Tubule fluid flows in opposite directions in the ______ & _____ _____
countercurrent multiplier
ascending & descending limbs
The loops increase _____ of interstitial fluid in a ______ way
osmolarity
graduated
Renal failure results in _____ & ______ retention (____ blood pressure), ______ retention (_____ poisoning), and ______ aka decreasing pH
salt & water retention (hbp)
urea retention
acidosis
Dialysis treatment passes blood through membrane channels bathed in a ______-____ solution to remove ______.