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Prevalence of Depersonalization-derealization disorder
- Most people experience transient symptoms
- Lifetime prevalence is 0.8% - 2.8%
- Both sexes
- Average age of onset is 16; decreases significantly with age (>5% after 25)
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Types of Depersonalization-derealization disorder
- Continuous symptoms
- Discrete recurring episodes
- Episodic, progressing to chronic
- All equal prevalence
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Depersonalization-derealization disorder etiology
- Neurotic and Introverted personality and associated cognitive causes
- Emotional abuse/neglect
- Witnessing violence, severe illness or death
- Stress, depression and anxiety
- Drugs
- Biological factors
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Treatment of Depersonalization-derealization disorder
- CBT and IBT (Interactive behav-... )
- Stress management
- Anxiety meds can have paradoxical effects
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Cortex functionality
- Planning
- Language
- Perception
- Memory
- Integration
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Limbic system functionality
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Midbrain functionality
Relays - Sensory and motor
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Hindbrain functionality
- Heart rate
- Breathing
- Digestion
- Sleep regulation
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Hippocampus involvement
- Emotion
- Memory
- Sensory information
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Thalamus involvement
Sensory relays (organ to cortex)
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Amygdala involvement
- Motivation
- Emotional control & interpretation
- Fear
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CRH
Corticotropin releasing hormone
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ACHT
Adrenocorticotropic hormone
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