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Neurons & Nervous System part 3
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a chemical synapse between motor neurons & skeletal muscle cells
neuromuscular junction
A motor neuron releases __ from its axon terminals.
acetylcholine (ACh)
The postsynaptic membrane of the muscle cell is the __
motor end plate
Voltages due to synaptic transmission & measured in the muscle are called __
Endplate Potentials (EPPs)
main neurotransmitters in the CNS
ACH
: in skeletal muscles & CNS
Glutamate
: an excitatory amino acid
Glycine & GABA
: inhibitory amino acids
Glutamate is __ and will result in __, but the __ of different receptors varies significantly
excitatory; depolarization; timing
__ receptors allow a rapid influx of Na+
AMPA
- an ionotropic glutamate receptor
__ receptors first require a slight depolarization through other receptors & allow a slower Na+ influx, as well as Ca2+
NMDA
- an ionotropic glutamate receptor
Neurotransmitters are cleared from the cleft after release in order to stop their action in several ways:
diffusion
reuptake by adjacent cells
Enzymes present in the cleft may destroy them.
ex. Acetylcholinesterase acts on ACh.
The postsynaptic cell must sum the __. Summation occurs at the __.
excitatory & inhibitory input; axon hillock
adds up messages at different synaptic sites
spatial summation
(details on page 899 in book)
adds up potentials generated at the same site over time
temporal summation
(details on page 899 in book)
Drugs treat the nervous system by modulating __
synaptic interactions
mimic or potentiate the effect of a neurotransmitter
agonists
block the actions of a neurotransmitter
antagonists
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Author
issacgoboom
ID
325203
Card Set
Neurons & Nervous System part 3
Description
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Updated
2016-11-01T22:16:23Z
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