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Anticoagulant/Antithrombolytic Drugs

  1. enoxaparin
    Lovenox
  2. dalteparin
    Fragmin
  3. tinzaparin
    Innohep
  4. fondaparinux
    Arixtra
  5. rivaroxaban
    Xarelto
  6. edoxaban
    Savaysa
  7. apixaban
    Eliquis
  8. argatroban
    Acova
  9. desirudin
    Iprivask
  10. bivalirudin
    Angiomax
  11. dabigatran
    Pradaxa
  12. warfarin
    Coumadin
  13. ticlopidine
    Ticlid
  14. clopidogrel
    Plavix
  15. prasugrel
    Effient
  16. ticagrelor
    Brilinta
  17. eptifibatide
    Integrelin
  18. tirofiban
    Aggrastat
  19. abciximab
    ReoPro
  20. vorapaxar
    Zontivity
  21. unfractionated heparin
    UFH
  22. alteplase
    Activase
  23. reteplase
    Retevase
  24. tenecteplase
    TNKase
  25. Name the Low Molecular Weight Heparins
    • enoxaparin (Lovenox)
    • daltaparin (Fragmin)
    • tinzaparin (Innohep)
  26. Name the Factor Xa inhibitors
    • fondaparinux (Arixtra)
    • rivaroxaban (Xarelto)
    • apixaban (Eliquis)
    • edoxaban (Savaysa)
  27. Name the Direct Thrombin Inhibitors
    • argatroban (Acova)
    • desirudin (Iprivask)
    • bivalirudin (Angiomax)
    • dabigatran (Pradaxa)
  28. Name the Vitamin K Agonists
    warfarin (Coumadin)
  29. Name the ADP Inhibitors
    • ticlopidine (Ticlid)
    • clopidogrel (Plavix)
    • prasugrel (Effient)
    • ticagrelor (Brilinta)
  30. Name the Glycoprotein IIb/IIIa Inhibitors
    • eptifibatide (Integrelin)
    • tirofaban (Aggrastat)
    • abciximab (ReoPro)
  31. Name the Thrombin Receptor Inhibitors
    vorapaxar (Zontivity)
  32. Name the Thrombolytics
    • alteplase (Activase)
    • reteplase (Retevase)
    • tenecteplase (TNKase)
  33. What NSAID is also an antiplatelet drug?
    Aspirin
  34. What is the number 1  adverse event of UFH?
    • Bleeding due to:
    • -Age
    • -recent surgery
    • -heavy alcohol consumption
    • -renal failure
    • -PUD
    • -Malignancy
  35. Define HAT (heparin associated Thrombocytopenia) and how does it differ from HIT (heparin induced thrombocytopenia).
    HAT is a transient benign decrease in platelets, rarely dipping below 100k platelets

    HIT is a rare and potentially fatal severe platelet fall of >50%  within 7-10 days
  36. What are the monitoring parameters of UFH?
    • aPTT
    • CBC
    • Hgb
    • Hct
    • plt
  37. What are the reversal strategies for UFH?
    1. Stop heparin immediately and administer FFP or PCC to restore coagulation factors

    2. protamine sulfate administered at 1 mg/50 units of heparin within 30 minutes of original admin of heparin
  38. Why is IM injection of heparin avoided?
    Due to increased risk of hematoma
  39. What is the "gold standard" imaging test for DVT?
    Venography - injection of radiopaque contrast dye into foot vein
  40. What is the "gold standard" imaging test for PE?
    pulmonary angiography - injection of contrast dye into pulmonary artery
  41. What lab test is used primarily to rule out DVT/PE?
    Negative D-Dimer result
  42. If a patient has a "massive PE" and is a high risk for bleeding, what would be considered for the follow up treatment?
    • 1. catheter directed thrombectomy
    • 2. LMWH/UFH/fondaparinux + Warfarin or DOAC (rivaroxaban, dabigatran, apixaban)
Author
mbailey585
ID
325096
Card Set
Anticoagulant/Antithrombolytic Drugs
Description
Anticoagulant/Antithrombolytic Drug Names, MOA, Indication
Updated

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