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Anticoagulant/Antithrombolytic Drugs
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enoxaparin
Lovenox
dalteparin
Fragmin
tinzaparin
Innohep
fondaparinux
Arixtra
rivaroxaban
Xarelto
edoxaban
Savaysa
apixaban
Eliquis
argatroban
Acova
desirudin
Iprivask
bivalirudin
Angiomax
dabigatran
Pradaxa
warfarin
Coumadin
ticlopidine
Ticlid
clopidogrel
Plavix
prasugrel
Effient
ticagrelor
Brilinta
eptifibatide
Integrelin
tirofiban
Aggrastat
abciximab
ReoPro
vorapaxar
Zontivity
unfractionated heparin
UFH
alteplase
Activase
reteplase
Retevase
tenecteplase
TNKase
Name the Low Molecular Weight Heparins
enoxaparin (Lovenox)
daltaparin (Fragmin)
tinzaparin (Innohep)
Name the Factor Xa inhibitors
fondaparinux (Arixtra)
rivaroxaban (Xarelto)
apixaban (Eliquis)
edoxaban (Savaysa)
Name the Direct Thrombin Inhibitors
argatroban (Acova)
desirudin (Iprivask)
bivalirudin (Angiomax)
dabigatran (Pradaxa)
Name the Vitamin K Agonists
warfarin (Coumadin)
Name the ADP Inhibitors
ticlopidine (Ticlid)
clopidogrel (Plavix)
prasugrel (Effient)
ticagrelor (Brilinta)
Name the Glycoprotein IIb/IIIa Inhibitors
eptifibatide (Integrelin)
tirofaban (Aggrastat)
abciximab (ReoPro)
Name the Thrombin Receptor Inhibitors
vorapaxar (Zontivity)
Name the Thrombolytics
alteplase (Activase)
reteplase (Retevase)
tenecteplase (TNKase)
What NSAID is also an antiplatelet drug?
Aspirin
What is the number 1 adverse event of UFH?
Bleeding due to:
-Age
-recent surgery
-heavy alcohol consumption
-renal failure
-PUD
-Malignancy
Define HAT (heparin associated Thrombocytopenia) and how does it differ from HIT (heparin induced thrombocytopenia).
HAT is a transient benign decrease in platelets, rarely dipping below 100k platelets
HIT is a rare and potentially fatal severe platelet fall of >50% within 7-10 days
What are the monitoring parameters of UFH?
aPTT
CBC
Hgb
Hct
plt
What are the reversal strategies for UFH?
1. Stop heparin immediately and administer FFP or PCC to restore coagulation factors
2. protamine sulfate administered at 1 mg/50 units of heparin within 30 minutes of original admin of heparin
Why is IM injection of heparin avoided?
Due to increased risk of hematoma
What is the "gold standard" imaging test for DVT?
Venography - injection of radiopaque contrast dye into foot vein
What is the "gold standard" imaging test for PE?
pulmonary angiography - injection of contrast dye into pulmonary artery
What lab test is used primarily to rule out DVT/PE?
Negative D-Dimer result
If a patient has a "massive PE" and is a high risk for bleeding, what would be considered for the follow up treatment?
1. catheter directed thrombectomy
2. LMWH/UFH/fondaparinux + Warfarin or DOAC (rivaroxaban, dabigatran, apixaban)
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Author
mbailey585
ID
325096
Card Set
Anticoagulant/Antithrombolytic Drugs
Description
Anticoagulant/Antithrombolytic Drug Names, MOA, Indication
Updated
2016-10-31T04:33:21Z
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