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Sensory cells transduce _____ and ______ stimuli into neuronal signals. Sensory transduction begins with a _____ _____ that can detect a specific stimulus. The receptor protein opens or closes ion channels in the membrane, changing the _____ ______
- physical and chemical
- receptor protein
- resting potential
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Two types of sensory receptor proteins are ______ & ______
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ionotorpic:
metabotropic:
- ionotropic: ion channels, or directly affected ion channels
- metabotropic: affect ion channels through g proteins and 2nd messengers
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3 examples of ionotropic
2 examples of metabotropic
- ionotropic: mechanoreceptors, thermoreceptors, electrosensors
- metabotropic: chemoreceptors, photoreceptors
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Receptor potential
graded membrane potentials that travel a short distance
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2 ways a receptor potential can generate an action potential
- • Can generate action potentials in the receptor cell
- • Can trigger release of neurotransmitter so that a downstream neuron generates an action potential
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Intensity of a sensation is coded as the frequency of _____ _____. Some sensory cells transmit info to the brain about internal conditions w/out ______ sensation
- action potentials
- conscious sensation
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Different messages from different sensory neurons are perceived according to what ____ ____ they are connected. Neuronal activity in the _____ _____ is perceived as sound. Even blind subjects report seeing light if their ____ ____ is stimulated DIRECTLY
- brain area
- auditory cortex
- visual cortex
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Adaptation
diminishing response to repeated stimulation
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_______ allows animals to ignore background but remain sensitive to changing or new stimuli. Name a sensory cell that doesnt display this phenomena
- adaptation
- mechanoreceptors for balance & pain
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List the 4 classifications of receptors by the stimulus detected
- chemoreceptors
- mechanoreceptors
- thermoreceptors
- nociceptors
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Chemoreceptors
also state what they monitor
receptor proteins that bind to various molecules, ligands; responsible for touch, taste and smell
monitor internal environ., such as CO2 lvls in blood
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mechanoreceptors respond to ______ forces
state 5 such forces
mechanical forces
- touch
- pressure
- stretch
- vibration
- itch
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thermoreceptors respond to _____ changes, chemoreceptors respond to _____ in solution, photoreceptors respond to ____ and are located in the _____, nociceptors respond to _____ stimuli that result in ______
- temp
- chemcial
- light
- eye
- harmful
- pain
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Olfaction is the sense of ______ and depends on _______ (type of receptor)
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Olfactory sensors are embedded in ______ tissue at the top of the _____ cavity (in vertebrates)
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Axons extend to the olfactory bulb in the brain, _____ end in olfactory hairs on the _____ epithelium
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An odorant is a molecule that activates an ______ ______ _____. Odorants bind to receptor proteins on the _____ ____.
- olfactory receptor protein
- olfactory cilia
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Middle ear is an ____ filled cavity. It is open to the throat via the ______ tube which equilibrates air pressure between _____ ___ & the ______
- air
- eustachian tube
- middle ear
- outside
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Name the ossicles.
They transmit vibrations of ____ _____ to the ____ ____
- malleus, incus, stapes
- tympanic membrane
- oval window
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Movement of oval window is translated into ____ changes in the fluid filled ____ ___
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Inner ear has two sets of canals, the _______ system for _____ and the _____ for _____
- vestibular system for balance
- cochlea for hearing
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The cochlea is a tapered and coiled chamber composed of three parallel canals separated by _______ membrane and the ______ membrane
- reissner's membrane
- basilar membrane
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The organ of corti sits on the ______ membrane. It transduces pressure waves into _____ _____
- basilar membrane
- action potentials
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The organ of corti contains hair cells w/ _______ and their tips are embedded in the ______ membrane. The hair cells bend and create a ______ potential that can alter _______ release
- stereocilia
- tectorial membrane
- graded potential
- transmitter
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Upper and lower canals of the _____ are joined distally.
cochlea
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round window
a flexible membrane at the end of the canal
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Pressure waves can travel all the way around to reach the _____ window or take a shortcut across the _____ membrane
- oval window
- basilar membrane
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conduction deafness
loss of function of tympanic membrane or ossicles
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nerve deafness
damage to inner ear or auditory nerve pathways (sheering of stereocilia)
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_____ cells in the organ of corti can be damaged by loud sounds. This damage is ______ and ______
- Hair
- cumulative & irreversible
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hair cells
mechanoreceptors in organs of hearing and equilibrium
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Hair cells have _____ called stereocilia. Bending of ______ opens or closes ion channels
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All animals that display photosensitivity use the same pigments called _______
rhodopsins
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Photoreceptor cells are _______ ______ cells that transform light into ______ _____
- metabotropic sensory
- action potentials
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Rod cells (3)
- outer segment
- inner segment
- synaptic terminal
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In rod cells, there is: the outer segment w/ discs of ____ ______containing ______ to capture photons. An inner segment that contains the _____ & _____. A synaptic terminal where the ____ cell communicates w/ other neurons
- plasma membrane
- rhodopsin
- nucleus & organelles
- rod
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Rhodposin molecules consist of _____ (a protein) and a light absorbing group ________. Rhodopsin sits in teh plasma membrane of a _______ cell
- opsin
- 11-cis-retinal
- photoreceptor cell
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When 11-cis-retinal absorbs photons of light it transforms into __________ and that changes the conformation of _____.
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Rod cell is a type of vertebrate _______, a _____ _____ that doesn't produce ____ _____
- photoreceptor
- modified neuron
- action potentials
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Rod cells release _______ from their bases where they synapse w/ an adjacent _____. Outer segment is a stack of plasma membrane discs packed with _______
- transmitter
- neuron
- rhodopsin
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The retina has five layers of neurons that receive info before sending it to the brain. Axons from ______ cells at the front of the _____ form the _____ nerve and send input to the _____. Neurons between the ______ cells and the _________ process info.
- ganglion cells
- retina
- optic nerve
- brain ganglion cells
- photoreceptors
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Photoreceptor cells are connected to gang cells via _____ cells. Changes in photoreceptor membrane potential in response to light alters their ________ release onto _____ cells
- bipolar cells
- transmitter
- bipolar cells
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Rate of photoreceptor neurotransmitter release affects rate of release from _____ cells onto _____ cells. This determines rate of action potentials from ganglion cells to the _____.
- bipolar cells
- ganglion cells
- brain
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