-
PROTON PUMP INHIBITORS (PPIs)
Mechanism of action
Side effects
- Prilosec, Nexium, Prevacid, Protonix
- Mechanism of action: Decrease HCL acid secretion, decrease irritation of the esophageal and gastric mucosa.
- Side effects: Headache, abdominal pain, nausea, diarrhea, vomiting, flatulence
-
HISTAMINE (H2 RECEPTOR BLOCKERS)
Mechanism of action
Side effects
- Tagamet, Zantac, Pepcid
- Mechanism of action: Blocks action of histamine on the H2 receptors to decrease HCL acid secretion. Decreases conversion of pepsiongen to pepsin. Decreases irritation of the esophageal and gastric mucosa.
- Side effects: Headache, abdominal pain, constipation, diarrhea
-
PHENOTHIAZINES
Trade names: T,T,C,S,P
Mechanism of action
Side effects
- Thorazine, Trilafon, Compazine, Stelazine, Phenergan
- Mechanism of action: Block dopamin receptors that trigger N/V
- Side effects: Dry mouth, hypotension, sedative effects, rashes, constipation.
-
ANTIHISTAMINES
Trade names: B,D,V,B
Mechanism of action
Side Effects
Bonine, Dramamine, Vistaril, Benadryl
Mechanism of action: Block histamine receptors that trigger N/V - Side effects: Dry mouth, hypotension, sedative effects, rashes, constipation.
-
PROKINETIC AGENTS
Trade names:M,R
Mechanism of action
Side effects
Motilium, Reglan
Mechanism of action: Inhibit action of Dopamine, increase gastric motility and emptying. - Side effects: CNS side effects ranging from Anxiety - hallucinations. Extrapyramidal effects: tremor and dyskinesias
- Note: given 2 min slowly
-
Serotonin (5 - HT3) Antagonists
Trade names: Z,A,K,A
Mechanism of action
Side effects
- Zofran, Anzemet, Kytril, Aloxi
- Mechanism of action: Block action of serotonin (substance that causes N/V)
- Side effects: Constipation, diarrhea, headache, fatigue, malaise, elevated liver function tests
-
ANTACIDS
Examples
Mechanism of action
Notes
- Aluminum carbonate, Aluminum hydroxide, Calcium carbonate (TUMS), Magnesium oxide, Sodium Bicarbonate (alka seltzer), Sodium Citrate (Bicitra)
- Mechanism of action: Neutralizes HCL acid
- Notes: short lived relief, take 1 - 3 hours after meals
-
IBD Drug Therapy
5 Aminosalicylates
examples: A, P, D, C
Action
- Azulfidine, Penasa, Dipentum, Colazal
- Action: Decrease GI inflammation through direct contact w/ bowel mucosa.
-
IBD drug therapy
Antimicrobials
Examples: F, C, B
Action
- Flagyl, Cipro, Biaxin
- Action: Prevent or treat infections
-
IBD drug therapy
Corticosteroids
Examples: P, E
Action
- Prednisone, Entocort
- Action: Decrease inflammation
-
IBD drug therapy
Immunosuppresants
Examples: I, M, C
Action
- Imuran, Methotrexate, Cyclosporine
- Action: Suppress immune response
-
IBD drug therapy
Biologics
Examples: R, H, C, S
Action
- Remicade, Humira, Cimzia, Simponi
- Action: Inhibit the cytokine tumor necrosis factor (TNF)
|
|
