N 207 - carbohydrates

  1. what are the different types of monosaccharides?
    • glucose: 6 membered ring and 6 carbon atoms (OH is down on C4)
    • galactose: 6 membered ring and 6 carbon atoms (OH is up on C4)
    • fructose : 5 membered ring and 6 carbon atoms
  2. what are the different types of disaccharides?
    • sucrose = fructose + galactose (in table sugar)
    • maltose = glucose + glucose (in beer)
    • lactose = glucose + galactose (milk/least sweet)
  3. what is a glycosidic bond?
    the bond that holds 2 glucose units together
  4. what is hydrolysis?
    • hydrolysis is a reaction that slips the molecule in 2
    • added H2O
  5. what are different types of polysaccharides?
    • starch : amylopectin and amylose
    • glycogen
    • celllulose
  6. what is glycogen?
    • storage form of energy in the body
    • made of glucose units
    • stored in the liver
    • short term glucose
    • liver cells produce glucose from glycogen to be sent directly to blood
    • muscle cells can also produce glucose from glycogen but must use it for themselves
  7. what are starches?
    • storage form of energy in plants
    • long chains of glucose 
    • amylose = unbranched
    • amylopectin = branched
    • influences cooking characteristics
  8. what is fibre/cellulose?
    provides in them, roots, leaves and skin of plants
  9. what do the mouth and salivary glands do to starch?
    • the salivary glands secrete saliva into the mouth to moisten the food
    • the salivary enzyme amylase begins digestion and hydrolyses the starch
    • Starch → small polysaccharides and maltose
  10. what does the stomach do?
    the stomach acids intactivate salivary enzymes, halting starch digestion
  11. what do the small intestine and pancreas do?
    • the pancreas produces amylase that is released through the pancreatic duct into the small intestine
    • Starch → small polysaccharides and maltose

    • then discharges enzymes on the surface of the small intestinal cells hydrolyze the disaccharides into monosaccharides
    •           
    • Maltose (by maltase) → glucose + glucose

    • Sucrose (by sucrase) → glucose + fructose
    • Lactose (by lactase) → glucose + galactose

    intestinal cells absorb these monosaccharides
  12. what does the mouth do to fiber?
    it mechanically crushes and breaks down the finer and mixes it with saliva to moisten it fr swallowing
  13. what does the stomach do to fiber?
    fiber is not digested and it delays gastric emptying
  14. what does the small intestine do to fiber?
    • fiber is not digested
    • it delays absorption of other nutrients
  15. what does the large intestine do to fiber?
    • fiber passes intact through the digestive tract to the large intestine
    • heres how the bacterial enzymes digest finer
    • Some fiber (by bacterial enzymes) → short chain fatty acids + gas
    • fiber holds water and regulates bowel activity
    • fiber binds to water and binds to substances like bile, cholesterol and some minerals and carries them out of the body
  16. how are monosaccharides absorbed?
    • 1. the monosaccharides enter the capillaries of the intestinal villi of the small intestine
    • 2. they travel to the liver via the portal vein
    • 3. in the liver, galactose and fructose are converted to glucose
  17. what is lactose intolerance?
    • lactose is not properly digested due to the lack of production of lactase on the brush border due to ageing or disease
    • NOT an allergy
    • undigested lactose can cause some symptoms like nausea, diarrhea, cramps, bloating, flatulence
    • it creates an osmotic effect : holds water in the lumen
    • solutions: milk with a mean, yogurt, cheese, lactose reduce milk, lactase pills
  18. what are the functions of glucose in the metabolism?
    • precursor for aa
    • converted to glycogen for energy storage (short term energy store)
    • converted to fat for energy storage (long term energy store)
    • oxidized for energy
    • prevents ketosis (accumulation of ketone bodies in the blood)
  19. what is glucose needed for?
    • brain cells
    • blood cells
    • spermatogenesis
    • mammary gland
    • fetus
  20. what is hypoglycemia?
    ↓ blood sugar concentration
  21. what is hyperglycemia?
    ↑ blood sugar concentration
  22. how does our body maintain blood glucose homeostasis when we eat?
    • 1. when a person eats, blood glucose ↑
    • 2. ↑ blood glucose stimulates the pancreas to release insulin into the blood
    • 3. insulin stimulates the uptake of glucose into cells and stage as glycogen in the liver and muscles
    • insulin also stimulates the conversion of excess glucose into fat for storage
  23. how does our body maintain blood glucose homeostasis post absorptive (after fed)?
    • 4. as the body uses glucose, blood levels decline ↓
    • 5. ↓ blood glucose stimulates the pancreas to release glucagon into the blood stream
    • 6. glucagon stimulates liver cells to break down glycogen and release glucose into the  blood
    • 7. blood glucose begins to rise ↑
  24. what is type 1 diabetes?
    • 10% of cases
    • high blood glucose
    • destructions of pancreatic cells
    • insulin secretion by the B cells of the pancreas is ineffective
    • autoimmune, viral
    • usually in children
    • treatment = exogenous insulin injections, low fat, low GI CHOs and fibre, balance diet and exercise
  25. what is type 2 diabetes?
    • 90% cases
    • high blood glucose
    • cell are not sensitive to insulin
    • "insulin resistance"
    • treatment = low fat, low GI CHOs and fibre, weight loss, exercise, diet
  26. how does it work??
    insert drawing
  27. how does a nephron work
  28. what is glycemic index
    its a method to classify foods according to their potential for raising blood glucose

    GI% = glycemic response to 50g of food x100% / glycemic response to 50g of glucose

    • lowering the glycemic index of the diet may improve blood lipids and reduce CVD risk
    • low glycemic diet can also help with weight management
  29. what are dental carries?
    • the decay of teeth
    • begins when acid dissolves the enamel that covers the tooth
    • if not repaired, the decay may penetrate the dentin and spread into the pulp of the tooth, accusing inflammation, abscess and possible loss of the tooth

    • sugars from foods and breakdown of starches contribute to tooth decay
    • bacteria ferment the sugars in the mouth and produce an acid that erodes tooth enamel causing dental carries
  30. what are some sugar replacers?
    • sugar alcohols like xylitol, mannitol, sorbitol
    • they're not fermentable and are slowly absorbed
    • about 2kcal/g
    • "sugar free" dow not mean "no cal"
  31. what is insoluble dietary fibre?
    • from cell walls
    • structural
    • less fermentable

    sources = cellulose, ligin, hemicellulose

    • actions in the body =
    • ↑ fecal weight and speed fecal passage through colon,
    • provide bulk and fullness


    • health benefits = alleviate constipation, 
    • ↓ risks of appendicitis,
    • hemorrhoids,
    • may help with weight management

    foods = fibrous veg, wheat bran
  32. what is dietary soluble fiber?
    • cement
    • glue from plants
    • more fermentable

    sources = pectin, gums, mucilages

    • Actions in the body
    • ↓ blood cholesterol by finding to bile,
    • slow glucose absorption,
    • slow transit of food through upper GI tract, hold moisture in stools,
    • softening them,
    • yield small fat molecules after fermentation that the colon can use for energy

    • Health benefits =
    • ↓ list of heart disease
    • ↓ risk of diabetes

    • foods = additives - carrageenan, guar gum (emulsifier), pectin in jams
    • beans, legumes, nuts, fruits, oats, barley
  33. how does fiber affect work in the small intestine?
    • its not digested by out enzymes
    • slows abosrption for better glycemic control

    • soluble fiber = binds bile acids 
    • ↓ enterohepatic circulation
    • ↓ fat, cholesterol and fat soluble vitamin absorption
    • ↓ cholesterol levels


    • insoluble fiber = binds cations
    • phytates ↓ Fe, Ca, Zn absorption
  34. enetrohepatic circulation
    insert
  35. what are the action of finer in the colon?
    • ↑ GI motility, speeds up transit
    • attracts water, bulk
    • ↓ constipation, diverticular disease, haemorrhoids 

    • fermented by intestinal bacteria
    • gas - CH4, H2, CO2
    • short chat FAs 
    • energy for colonocytes
    • binds bile acids and toxicants - protects colon
  36. what are the dietary recommendations for finer?
    current intake = 20-25g/d

    • AI for finer base don energy intake:
    • 38g/day for men
    • 25g/d for women

    NO UL FOR FIBER
  37. what are the health effects of low GI foods and fiber ?
    • 1. weight control
    • foods tend to be ↓ in fat and ↑ satiety and bulk


    • 2. heart disease
    • ↓ in saturated fat, ↑ in phytochemical
    • ↓ cholesterol


    • 3. cancer
    • ↓ colon cancer risk,  ↓ pH phytochemical, vitamins


    • 4. diabetes
    • glycemic control
    • weight control

    5. GI health
Author
K.A
ID
324585
Card Set
N 207 - carbohydrates
Description
nutr
Updated