Pharm-Comprehensive Review

Chemical used to diagnose, treat or prevent disease

Study of drugs & their interaction w/ the body

Broad group to which a drug belongs

Conditions that make the admission of a drug appropriate

How a drug interacts with the body to cause its effect

The drugs untoward or undesired effects

Conditions that make it inappropriate to give the drug

Drugs that may deform or kill a fetus

How a drug is absorbed, distributed, metabolized or excreted

Force of attraction between drug & receptor

Drugs ability to cause the expected response

Drug which binds to receptor site causing a desired effect

Drug which binds w/ a receptor site blocking it but not causing the desired effect

Aka hypersensativity, the effect occurs as a drug is antigenic & activates immune sys

An allergic reaction isnt necessarily life threatening where as anaphylaxis is

Decreased response to the same amt of drug after repeated administrations

Tolerance for a drug that develops after administration of a different drug. ie opiod b/c tolerance for 1 = tolerance for all

Rapidly occurring tolerance to a drug. May occur aft a single dose

^ effectiveness when a drug is given in several doses

Pt becomes accustomed to the drugs presence in his body & will suffer physical or psychological withdrawal symptoms upon its absence

The effects of 1 drug alters the response to another drug

The effects of 1 drug block the response to another drug

• Additive effect
• 2 drugs w/ same effect given together. 1+1=2

2 drugs given together having the same effect & producing a response > the sum of their individual responses. 1+1=3

• 1 drug enhances the effect of another
• ie Promethazine enhances morphine

Direct biochemical interaction between 2 drugs; 1 drug effects the pharm of another

Absence of the sensation of pain

Induces loss of sensation to touch or pain

State of decreased anxiety & inhibition

Instigation of sleep

Causes effects like the parasympathetic NS (cholinergics)

Blocks the parasympathetic nervous sys

Causes effects like those of the sympathetic NS

Blocks the action of the sympathetic sys

Drug used to treat or prevent abnormal cardiac rhythms

• High abuse potential
• No med indication

• High abuse potential
• May lead to dependance

• Less abuse
• Moderate dependance

• Low abuse
• Less dependance

• Low abuse
• Limited dependance

Conditions for which there is evidence &/or general agreement that a given procedure or treatment is useful & effective

Conditions for which there is conflicting evidence &/or a divergence of opinion about the usefulness/efficacy of a procedure or treatment

Weight of evidence/opinion is in favor of usefulness/efficacy

Usefulness/efficacy is less well established by evidence/opinion

Conditions for which there is evidence &/or general agreement the the procedure/treatment is nor useful/effective & in some cases may harmful