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Pharm-Comprehensive Review
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Drug
Chemical used to diagnose, treat or prevent disease
Pharmacology
Study of drugs & their interaction w/ the body
Classification
Broad group to which a drug belongs
Indication
Conditions that make the admission of a drug appropriate
Pharmacodynamics
How a drug interacts with the body to cause its effect
Side effect
The drugs untoward or undesired effects
Contraindication
Conditions that make it inappropriate to give the drug
Teratogenic Drug
Drugs that may deform or kill a fetus
Pharmacokinetics
How a drug is absorbed, distributed, metabolized or excreted
Affinity
Force of attraction between drug & receptor
Efficacy
Drugs ability to cause the expected response
Agonist
Drug which binds to receptor site causing a desired effect
Antagonist
Drug which binds w/ a receptor site blocking it but not causing the desired effect
Allergic Reaction
Aka hypersensativity, the effect occurs as a drug is antigenic & activates immune sys
What is the difference between anaphylaxis & an allergic reaction?
An allergic reaction isnt necessarily life threatening where as anaphylaxis is
Tolerance
Decreased response to the same amt of drug after repeated administrations
Cross tolerance
Tolerance for a drug that develops after administration of a different drug. ie opiod b/c tolerance for 1 = tolerance for all
Tachyphylaxis
Rapidly occurring tolerance to a drug. May occur aft a single dose
Cumulative Effect
^ effectiveness when a drug is given in several doses
Drug Dependance
Pt becomes accustomed to the drugs presence in his body & will suffer physical or psychological withdrawal symptoms upon its absence
Drug Interaction
The effects of 1 drug alters the response to another drug
Drug Antagonism
The effects of 1 drug block the response to another drug
Summation (aka ____ ____)
Additive effect
2 drugs w/ same effect given together. 1+1=2
Synergism
2 drugs given together having the same effect & producing a response > the sum of their individual responses. 1+1=3
Potentiation
1 drug enhances the effect of another
ie Promethazine enhances morphine
Interference
Direct biochemical interaction between 2 drugs; 1 drug effects the pharm of another
Analgesic
Absence of the sensation of pain
Anesthetic
Induces loss of sensation to touch or pain
Sedation
State of decreased anxiety & inhibition
Hypnosis
Instigation of sleep
Parasympathomimetic
Causes effects like the parasympathetic NS (cholinergics)
Parasympatholytic
Blocks the parasympathetic nervous sys
Sympathomimetic
Causes effects like those of the sympathetic NS
Sympatholytic
Blocks the action of the sympathetic sys
Antidysrhythmic
Drug used to treat or prevent abnormal cardiac rhythms
What is a schedule I drug?
High abuse potential
No med indication
Describe a schedule II drug.
High abuse potential
May lead to dependance
Describe a schedule III drug.
Less abuse
Moderate dependance
Describe a schedule IV drug.
Low abuse
Less dependance
Describe a schedule V drug.
Low abuse
Limited dependance
What are class 1 recs as per the AHA?
Conditions for which there is evidence &/or general agreement that a given procedure or treatment is useful & effective
What are class 2 AHA recs mean?
Conditions for which there is conflicting evidence &/or a divergence of opinion about the usefulness/efficacy of a procedure or treatment
What are class 2a rec as per the AHA?
Weight of evidence/opinion is in favor of usefulness/efficacy
What are class 2b recs as per the AHA?
Usefulness/efficacy is less well established by evidence/opinion
What are class 3 recs as per the AHA?
Conditions for which there is evidence &/or general agreement the the procedure/treatment is nor useful/effective & in some cases may harmful
Author
medic11
ID
32435
Card Set
Pharm-Comprehensive Review
Description
Pharm comprehensive review
Updated
2010-09-02T18:15:20Z
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