Pharmacology Ch 6 Dr Brown: Respiratory drugs

  1. Administrating a drug by a mist that is inhaled
    Nebulization therapy
  2. Mechanism that traps inhaled particles in a mucus layer and moves it up and out of the respiratory tree
    Mucociliary apparatus
  3. Pulmonary disease that in turn causes cardiac disease
    Cor pulmonale
  4. Type of drug that suppresses cough
  5. Type of drug that does not break apart mucus but increases watery secretions into the lungs
  6. Specific receptor that when stimulated causes bronchodilation
  7. Term meaning difficult breathing
  8. Definition of MDL
    Metered-dose inhaler
  9. Expectorant; works by irritating the gastric lining
  10. Centrally acting opioid antitussive; only FDA approved vet product for cough
  11. Same drug group as caffeine and theobromine in chocolate; a bronchodilator that contains 80% active ingredient and 20% salt
  12. Used in patients in which the inflammatory process is life threatening; not to be used with respiratory fungal disease; stabilizes cellular membranes more than antihistamines
    • Glucocorticoids
    • Corticosteroids
  13. Mucolytic drug that breaks apart sulfhydryl bonds
  14. Prophylactic antiinflammatory that decreases inflammatory response only if its at the site of inflammation before inflammation starts
  15. Potent narcotic antitussive; human product; C-III drug
  16. Type of drug used to decrease pulmonary edema
  17. Common antitussive ingredient in OTC cold preparations; not a controlled substance; not very effective in animals
  18. Also used as an IV administered muscle relaxant for equines
  19. Also used as an antidote in cats with acetaminophen toxicosis
  20. Active ingredient of aminophylline
  21. Used to dilate bronchioles by directly stimulating B2 receptors
    • Albuterol
    • Terbutaline
  22. TRUE OR FALSE: Inflammation and migration of inflammatory cells cause the mucus to become more sticky or viscous
  23. TRUE OR FALSE: Rapid breathing is called dyspnea
  24. TRUE OR FALSE: Inspissated mucus means that the mucus is dried out
  25. TRUE OR FALSE: Use of a diuretic drug would decrease the efficiency of the mucociliary apparatus
  26. TRUE OR FALSE: Dextromethorphan is more effective than hydrocodone as an antitussive
  27. TRUE OR FALSE: In dehydrated animals the cough is usually nonproductive
  28. TRUE OR FALSE: Common side effect of most direct bronchodilators is decreased heart rate and force of cardiac contraction
  29. TRUE OR FALSE: If an animal is in distress from bronchoconstriction, antihistamine drugs should be used to dilate the bronchioles
  30. TRUE OR FALSE: Decongestants primarily work by causing vasoconstriction in the nasal mucosa
  31. TRUE OR FALSE: Prescribing dextromethorphan antitussive requires a CS license
  32. TRUE OR FALSE: Nebulization describes the process by which macrophages move into the alveoli and clean up debris that made it down that far
  33. TRUE OR FALSE: Stimulation of the larynx produces a more forceful and gagging cough than bronchiolar irritation
  34. TRUE OR FALSE: Theophylline is the active ingredient and aminophylline is theophylline plus salt
  35. TRUE OR FALSE: Stimulation of the parasympathetic system in the bronchioles causes bronchoconstriction
  36. TRUE OR FALSE: Centrally acting cough suppressants work better in vet patients than locally acting ones
  37. TRUE OR FALSE: Overdose of the opioid narcotic antitussives causes respiratory depression
  38. TRUE OR FALSE: Drugs that stimulate acetylcholine receptors in the respiratory tree cause bronchodilation
  39. TRUE OR FALSE: Stimulation of H1 receptors on the bronchioles produces an effect opposite of what stimulation of B2 receptors would do to the bronchioles
  40. TRUE OR FALSE: Butorphanol and hydrocodone are CS
  41. Stimulation of which brand of the autonomic nervous system produced bronchodilation?
    Sympathetic nervous system
  42. Stimulation of which specific receptor causes vasoconstriction and is the receptor involved with the mechanism of action of decongestants?
  43. What effect do methylxanthines have on the CNS?
    Stimulate CNS
  44. What substance is released by mast cells and causes inflammation and bronchoconstriction?
  45. What type of cough brings mucus?
    Productive cough
  46. What type of drug has a name that means cause to spit?
  47. Preventing foreign particles from entering and causing damage or inflammation
  48. Reduces coughing by directly soothing the respiratory mucosal irritation that is initiating the cough
    Locally acting antitussive
  49. Horses with what disease may be treated with aersolized corticosteroids?
    Chronic obstructive pulmonary disease
  50. Butorphahol
    Use, contraindications, side effects
    • Use: Antitussive, analgesic 
    • Cons: Liver disease, hypothyroidism, renal insufficiency
    • Side effects: Sedation, ataxia, anorexia
  51. Hydrocodone
    Use, contraindications, side effects
    • Use: Antitussive, kennel  cough
    • Cons: Hypersensitivity to narcotics
    • Side effects: Sedation, constipation, vomiting
  52. Acetylcysteine
    Use, how it works, side effects
    • Use: Mucolytic 
    • How it works: Thins/dissolves mucus so it can be coughed up
    • Side effects: Hives
  53. Guaifenesin 
    Use, how it works, contraindications, side effects
    • Use: Expectorant
    • How it works: Loosen congestion
    • Cons: Allergic 
    • Side effects: Dizziness, vomiting
  54. Albuterol
    Use, how it works, contraindications, side effects
    • Use: Bronchodilator
    • How it works: Relaxes muscles in the airway
    • Cons: Diabetes, hyperthyroidism, seizures, cardiac disease
    • Side effects: CNS excitement & dizziness
  55. Theophylline and Aminophylline
    Use, how it works, contraindications, side effects
    • Use: Bronchodilators 
    • How it works: Relaxes muscles in lungs/chest
    • Cons: Pregnant, severe heart disease, 
    • Side effects: Restlessness, stomach upset
Card Set
Pharmacology Ch 6 Dr Brown: Respiratory drugs
Ch 6 respiratory drug