Pharmacology Ch 6 Dr Brown: Respiratory drugs

Administrating a drug by a mist that is inhaled

Mechanism that traps inhaled particles in a mucus layer and moves it up and out of the respiratory tree

Pulmonary disease that in turn causes cardiac disease

Type of drug that suppresses cough

Type of drug that does not break apart mucus but increases watery secretions into the lungs

Specific receptor that when stimulated causes bronchodilation

Term meaning difficult breathing

Definition of MDL

Expectorant; works by irritating the gastric lining

Centrally acting opioid antitussive; only FDA approved vet product for cough

Same drug group as caffeine and theobromine in chocolate; a bronchodilator that contains 80% active ingredient and 20% salt

Used in patients in which the inflammatory process is life threatening; not to be used with respiratory fungal disease; stabilizes cellular membranes more than antihistamines

Mucolytic drug that breaks apart sulfhydryl bonds

Prophylactic antiinflammatory that decreases inflammatory response only if its at the site of inflammation before inflammation starts

Potent narcotic antitussive; human product; C-III drug

Type of drug used to decrease pulmonary edema

Common antitussive ingredient in OTC cold preparations; not a controlled substance; not very effective in animals

Also used as an IV administered muscle relaxant for equines

Also used as an antidote in cats with acetaminophen toxicosis

Active ingredient of aminophylline

Used to dilate bronchioles by directly stimulating B2 receptors

TRUE OR FALSE: Inflammation and migration of inflammatory cells cause the mucus to become more sticky or viscous
True False

TRUE OR FALSE: Rapid breathing is called dyspnea
True False

TRUE OR FALSE: Inspissated mucus means that the mucus is dried out
True False

TRUE OR FALSE: Use of a diuretic drug would decrease the efficiency of the mucociliary apparatus
True False

TRUE OR FALSE: Dextromethorphan is more effective than hydrocodone as an antitussive
True False

TRUE OR FALSE: In dehydrated animals the cough is usually nonproductive
True False

TRUE OR FALSE: Common side effect of most direct bronchodilators is decreased heart rate and force of cardiac contraction
True False

TRUE OR FALSE: If an animal is in distress from bronchoconstriction, antihistamine drugs should be used to dilate the bronchioles
True False

TRUE OR FALSE: Decongestants primarily work by causing vasoconstriction in the nasal mucosa
True False

TRUE OR FALSE: Prescribing dextromethorphan antitussive requires a CS license
True False

TRUE OR FALSE: Nebulization describes the process by which macrophages move into the alveoli and clean up debris that made it down that far
True False

TRUE OR FALSE: Stimulation of the larynx produces a more forceful and gagging cough than bronchiolar irritation
True False

TRUE OR FALSE: Theophylline is the active ingredient and aminophylline is theophylline plus salt
True False

TRUE OR FALSE: Stimulation of the parasympathetic system in the bronchioles causes bronchoconstriction
True False

TRUE OR FALSE: Centrally acting cough suppressants work better in vet patients than locally acting ones
True False

TRUE OR FALSE: Overdose of the opioid narcotic antitussives causes respiratory depression
True False

TRUE OR FALSE: Drugs that stimulate acetylcholine receptors in the respiratory tree cause bronchodilation
True False

TRUE OR FALSE: Stimulation of H1 receptors on the bronchioles produces an effect opposite of what stimulation of B2 receptors would do to the bronchioles
True False

TRUE OR FALSE: Butorphanol and hydrocodone are CS
True False

Stimulation of which brand of the autonomic nervous system produced bronchodilation?

Stimulation of which specific receptor causes vasoconstriction and is the receptor involved with the mechanism of action of decongestants?

What effect do methylxanthines have on the CNS?

What substance is released by mast cells and causes inflammation and bronchoconstriction?

What type of cough brings mucus?

What type of drug has a name that means cause to spit?

Preventing foreign particles from entering and causing damage or inflammation

Reduces coughing by directly soothing the respiratory mucosal irritation that is initiating the cough

Horses with what disease may be treated with aersolized corticosteroids?

Butorphahol
Use, contraindications, side effects

Hydrocodone
Use, contraindications, side effects

Acetylcysteine
Use, how it works, side effects

Guaifenesin 
Use, how it works, contraindications, side effects

Albuterol
Use, how it works, contraindications, side effects

Theophylline and Aminophylline
Use, how it works, contraindications, side effects