physio 2

  1. Electrical synapse characteristics
    • Two neurons linked together by gap junctions
    • Bidirectional communication
    • Ions or second messengers
    • Rapid communication
    • e.g retina, cortex, cardiac muscle
  2. Chemical synapses characteristics
    • Narrow space in between
    • Unidirectional
    • Neurotransmitters
    • Usually synapse on dendrites(e.g axodendritic:  axon to dendrites)
  3. Describe Signal transduction across the chemical synapse
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  4. Function: causes depolarization, closer to threshold
    Excitatory postsynaptic potential
  5. Define divergence
    Single neuron communicates to several other neurons
  6. Function: Causes hyperpolarization, further away from threshold
    Inhibitory postsynaptic potential
  7. Define Convergence
    Single neuron receives communication from different neurons
  8. Define summation
    • When threshold is reached: Action potential
    • When threshold is not reach: No action potential will occur.
    • (All or none properties of action potential)
  9. Steps in Acetylcholine synthesis
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  10. Steps in Acetylcholine breakdown (degradation)
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  11. What are 2 types of Acetylcholine receptors
    • Nicotinic cholinergic receptor
    • Receptor can bind to both acetylcholine and nicotine
    • Ionotropic= Channel-linked receptor- Excitatory postsynaptic potential
    • e.g increase muscle contractility
    • Muscarinic cholinergic receptor
    • Receptor can bind to both acetylcholine and muscarine drug
    • Metabotropic= G-protein coupled receptor
    • can be excitatory or inhibitory depending on the receptor subtypes
Card Set
physio 2