Atherosclerosis

What type of disorder is atherosclerosis?

Treatments used to be limited to?

Main layers of a normal artery from innermost to outermost

The layers of the artery are actually thick enough to have their own supply. This is done by ____ ____

What type of cells make up the individual layers of the artery?

The flaw of lipids that plays into the development of atherosclerosis

Which proteins provide the necessary task of lipid transport?

Apolipoproteins are produced by the ____. Name three types

____ are wrongfully called bad cholesterol and ____ are wrongfully called good cholesterol. What is their relation to cholesterol?

The endothelial layer has receptors for ___ and distributes them throughout the ________ layer where they accumulate.

As LDLs metabolize cells they encounter it attracts a group of white blood cells: ______/______. The _____ consume lipids containing cholesterol and swell into ____ ____ as they accumulate lipids

As macrophages turn into foam cells, the begin to release ____ like IL1 which is a form of _____ _____.

What attracts smooth muscle cells?

What is the result of the accumulation of foam and smooth muscle cells?

What happens to the bulge formed from the accumulation of foam cells and smooth muscle cells?

If the arterial bulge ruptures it will expose the contents of the underlying subendothelial layer like ____ & ___ _____ ____. What do they induce?

Where do formed blood clots actually begin to run into trouble?

People who exercise often produce more ____, this helps reduce the accumulation of _____ in the subendothelial layer. What is the result?

Exercise can be used to prolong the development of _______. Some studies say it even reduces the size of _____. However, there is a limit to how many ____ will be produced.

Treatment for atherosclerosis now includes:

The mutant lipoprotein that can be successfully used to treat atherosclerosis but never caught on due to the unattractive prospect of multiple daily injections