Therapeutic drug monitoring

  1. Class 1 rapid sodium channel blockers
    • Quinidine
    • Procainamide
    • Lidocaine
  2. Class 2 beta receptor blockers
    Propanolol
  3. Class 3 Potassium channel blockers
    Amiodarone
  4. Class 4 calcium channel blockers
    Verapamil
  5. Cardiactive drugs
    • Digoxin
    • Lidocaine
    • Quinidine
    • Procainamide
    • Disopyramide
    • Propanolol
    • Amiodarone
    • Verapamil
  6. Antibiotics
    • Aminoglycosides
    • Vancomycin
    • Chloramphenicol
  7. Antiwpileptic drugs
    • Phenobarbital
    • Phebytoin (dilantin)
    • Valproic acid (Depakene)
    • Carbamazepine (Tegretol) 
    • Ethosuximide (Zarontin)
    • Gabapentin (Neurontin)
    • Topiramate
    • Lamotrigine
    • Felbamate
  8. Psychoactive drugs
    • Lithium
    • Trcyclic antidepressants
    • Fluoxetine (Prozac)
  9. Bronchodilator
    Theophylline
  10. Immunosupressive drugs
    • Cyclosporine
    • Tacrolimus
    • Rapamycin
    • Mycophenolate moferil
    • Leflunomide
  11. Antineoplastic drugs
    • Methotrexate
    • Busulfan
  12. Anti-inflammatory/Analgesics
    • Salicylates/Aspirin
    • Acetaminophen (Tylenol)
    • Ibuprofen
  13. Cardiac glycoside for tx of atrial arrhythmia and CHF.
    Influenced by serum electrolytes
    Digoxin
  14. Corrects ventricular arrhythmia for tx of AMI
    Lidicaine (Xylocaine)
  15. Lidocaine is administered by
    • IV infusion
    • Because in oral complete hepatic removal of the absorbed drug)
  16. Quinidine
    Naturally occuring drug for the tx of arrhythmia
  17. Is used to tx ventricular arrhythmia
    GIT absorption is rapid and conplete
    Procainamide
  18. Substitute for quinidine
    Disopyramide
  19. Tx of angina pectoris, hypertension, coronary artery disease.
    Supresses conversion of T4 to T3
    Propanolol
  20. Tx for ventricular arrhytmias
    Iodine containing drugs. Can cause thyroid dysfunction
    Amiodarone
  21. For tx of angina, hypertension, and supraventricular arrhythmias.
    Verapamil
  22. Ttx for gram neg infxn 
    Administered IM or IV
    • Aminoglycosides
    • Gentamycon, tobramycin, amikacin, kanamycin, neomycin, streptomycin
  23. Is a glycopeptide effective against Gram positive cocci and bacilli
    Vancomycin
  24. It distributes to all tse, and it concentrates in the CSF
    Chloramphenicol
  25. Long acting barbiturate that controls grand mal tonic seizure and focal epilileptic; not used for petit mal seizure.
    Tx withdrawal symptoms in infants.
    Tx congenital hyperbilirubinemia
    Phenobarbital
  26. Control seizures; a short term prophylactic agent in brain injury
    Not used for petit mal and atomic seizures.
    Phenytoin (Dilantin)
  27. Used for tx of petit mal, atomuc seizures and grand mal.
    Valproic scid (Depakene)
  28. Carbamazepine (Tegretol)
    • It is a trycyclic compound related to imipramine
    • Effective for grand mal and tx seizures accompanied by pain.
  29. The drug of choice for controlling petit mal (absence) seizure
    Ethosuximide(Zarontin)
  30. It is chemically similar to neurotransmitter (GABA)
    Used for partial seizure
    Gabapentin
  31. Used for tx of manic depressive illness (bipolar disorders)
    Prevention of chronic cluster headache
    Lithium
  32. Used for tx of depression, insomia, extreme apathy and loss of libido.
    Tricyclic anridepressants (TCAs)
  33. Blocks the reuptake of serotonin in central serotonergic pathways
    Tx for OCD
    Fluoxetine (Prozac)
  34. Specific to the relaxation of bronchial smooth muscle.
    Theophylline
  35. Inhibits the cellular immune response by blocking production of interleukin-2
    To prevent rejection of allogenic organ transplants
    Supression of acute GVHD
    Cyclosporine
  36. 100x powerful than cyclosporine
    Tacrolimus
  37. Similar to tacrolimus major side effects are lipid abnormalities and thrombocytopenia
    Rapamycin
  38. Decreases renal allograft rejection
    Mycophenolate mofetil
  39. Leflunomide
    It inhibits lymphocyte proliferation; for tx of rheumatoid arthritis
  40. Inhibits DNA synthesis in all cells, by blocking dihydrofolate reductase
    Methotrexate
  41. Reverse the action of methotrexate
    Leucovorin
  42. An alkalyting agent used to treat leukemias and lymphomas prior to bone marrow transplantation
    Busulfan
Author
DeanRegentJoshua
ID
322295
Card Set
Therapeutic drug monitoring
Description
Clinical Chemistry by Rodriguez
Updated