1. Afil
    • avanafil
    • sildenafil
    • tadalafil
    • vardenafil
  2. "Afil"
    Medication Classification: Phosphodiesterase Type 5 (PDE5) Inhibitors
    • Select Prototype Medications: sildenafil (Viagra)
    • ●● Other Medications:
    • tadalafil (Cialis),
    • vardenafil (Levitra)
  3. "Afil"
    therapeutic uses:
    • Erectile dysfunction
    • nitric oxide released during sexual stimulation, resulting in enhanced blood flow to the corpus cavernosum and penile erection.
  4. Adverse affect: "Afil"
    • MI, sudden death
    • (Monitor risk factors and history with regard to cardiovascular health)
    • Priapism
    • (Instruct clients to notify the provider if erection lasts more than 4 hr.)
  5. Contraindications/Precautions "Afil"
    • Contraindicated in clients taking any medications in the nitrate family, such as nitroglycerin.
    • ●● Use cautiously in clients who have cardiovascular disease, including QT prolongation.
    • ●● Advise clients that grapefruit juice may increase plasma concentrations and possible adverse effects of medication.
  6. Medication/Food Interactions: "Afil"
    • Organic nitrates, such as nitroglycerin (Nitrostat)and isosorbide dinitrate (Isordil), can lead to fatal hypotension.
    • (Discourage concurrent use of organic nitrates oralpha blockers.)
    • Ketoconazole, erythromycin, cimetidine, ritonavir,and grapefruit juice inhibit metabolism of sildenafil,thereby increasing plasma levels of medication.
    • (Use these medications cautiously in clients takingPDE5 inhibitors.)
  7. -asone
    • betamethasone
    • dexamethasone
    • diflorasone
    • fluticasone
    • mometasone
  8. -Asone
    Glucocorticoid (Corticosteroids)
  9. -Asone
    Fluticasone (flovent)
    Mometasone furoate
    • Part of inhalation
    • prevents inflammation, suppress airway mucus production, promote response to Beta 2 receptor
    • Does not provide immediate effect, but rather promotes decrease frequency and severity of exacerbation and acute attack
  10. -Asone
    Dexamethasone (Decadron)
    Glucocorticoid use in combination with other antiemetic to treat chemotherapy-induced nausea and vomiting (CINV)
  11. -Asone
    Dexamethasone (Decadron)
    adverse effect:
    • Adrenal insufficiency(hypotension, dehydration, weakness, lethargy, vomiting, diarrhea associated with prolonged use)
    • (Advise clients to observe for indications and to notify the provider if they occur.)
    • Osteoporosis
    • (Advise clients to take calcium supplements, vitamin D, and/or bisphosphonate (alendronate [Fosamax]).
Card Set
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